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CNR1

CNR1(Cannabinoid Receptor 1),也稱為CB1受體,是一種七膜跨越型蛋白質(zhì)受體(G蛋白耦聯(lián)受體),其結(jié)構(gòu)包括一個(gè)胞外N端、跨膜區(qū)域以及一個(gè)胞漿C端。,屬于大麻素受體家族。CB1受體主要分布在中樞神經(jīng)系統(tǒng)(大腦和脊髓)中,它是大麻素(cannabinoid)分子的主要作用靶點(diǎn)之一。CNR1在中樞神經(jīng)系統(tǒng)中發(fā)揮著重要作用,參與了多種生理過(guò)程,包括疼痛感知、情緒調(diào)節(jié)、記憶和認(rèn)知功能。CNR1也在免疫系統(tǒng)中發(fā)揮一定作用。激活CB1受體可以抑制免疫細(xì)胞的活化和炎癥反應(yīng),因此CB1受體激動(dòng)劑有時(shí)被研究用于治療炎癥性疾病,在生物學(xué)和醫(yī)學(xué)研究中具有重要意義。

更多相關(guān)閱讀:CNR1(CB1):內(nèi)源性大麻素系統(tǒng)ECS經(jīng)典受體,為糖脂代謝和腫瘤注入全新研究?jī)r(jià)值!

熱銷產(chǎn)品

Recombinant Human Cannabinoid receptor 1(CNR1)-VLPs (Active) CSB-MP005678HU

驗(yàn)證數(shù)據(jù)

WB
CSB-MP005678HU WB

CSB-MP005678HU is detected by Mouse anti-6*His monoclonal antibody.

ELISA
High Purity Validated of CSB-MP005678HU

Activity: Measured by its binding ability in a functional ELISA. Immobilized Human CNR1 at 10 μg/ml can bind Anti-CNR1 recombinant antibody (CSB-RA005678MA01HU), the EC50 is 41.72-63.54 ng/mL.

CNR1 Recombinant Monoclonal Antibody CSB-RA005678MA01HU

驗(yàn)證數(shù)據(jù)

ELISA
High Purity Validated of CSB-RA005678MA01HU

The Binding Activity of Huamn CNR1 with Anti-CNR1 recombinant Antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human CNR1(CSB-MP005678HU) at 10 μg/mL can bind Anti-CNR1 recombinant antibody, the EC50 is 41.72-63.54 ng/mL.

CNR1 Antibodies

CNR1 for Homo sapiens (Human)

CNR1 Proteins

CNR1 Proteins for Homo sapiens (Human)

CNR1 Proteins for Rattus norvegicus (Rat)

CNR1 Proteins for Mus musculus (Mouse)

CNR1 Proteins for Felis catus (Cat) (Felis silvestris catus)

CNR1 Proteins for Taeniopygia guttata (Zebra finch) (Poephila guttata)

CNR1 Proteins for Zea mays (Maize)

CNR1 Proteins for Rana esculenta (Edible frog) (Pelophylax esculentus)

CNR1 Proteins for Pan troglodytes (Chimpanzee)

CNR1 Proteins for Macaca mulatta (Rhesus macaque)

CNR1 Proteins for Xenopus laevis (African clawed frog)

CNR1 Proteins for Taricha granulosa (Roughskin newt)