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FAS

FAS,即腫瘤壞死因子受體超家族成員6,別名APO-1、CD95、TNFRSF6,是一種細(xì)胞表面死亡受體,屬于腫瘤壞死因子受體超家族。FAS主要多種組織細(xì)胞表面表達(dá),少量以可溶性形式存在于血漿中。
FAS通過(guò)與其配體FasL結(jié)合,形成死亡誘導(dǎo)信號(hào)復(fù)合物(DISC),進(jìn)而激活下游的caspase凋亡級(jí)聯(lián)反應(yīng),引起細(xì)胞凋亡。FAS在免疫系統(tǒng)中發(fā)揮重要作用,特別是在細(xì)胞凋亡、免疫耐受和抗腫瘤免疫應(yīng)答中。FAS信號(hào)通路的異?;罨蛞种婆c多種疾病相關(guān),包括自身免疫性疾病、某些類(lèi)型的癌癥以及免疫缺陷疾病。

熱銷(xiāo)產(chǎn)品

Recombinant Human Fatty acid synthase (FASN), partial (CSB-EP008435HU)

驗(yàn)證數(shù)據(jù)

CSB-EP008435HU

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

FASN Recombinant Monoclonal Antibody (CSB-RA240595A0HU)

驗(yàn)證數(shù)據(jù)

CSB-RA240595A0HU

Immunofluorescence staining of Hela Cells with CSB-RA240595A0HU at 1:50, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeated by 0.2% TritonX-100, and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4℃. Nuclear DNA was labeled in blue with DAPI. The secondary antibody was FITC-conjugated AffiniPure Goat Anti-Rabbit IgG (H+L).

CSB-RA240595A0HU

Overlay histogram showing A549 cells stained with CSB-RA240595A0HU (red line) at 1:50. The cells were fixed with 70% Ethylalcohol (18h) and then incubated in 10% normal goat serum to block non-specific protein-protein interactions followedby the antibody (1μg/1*106 cells) for 1 h at 4℃.The secondary antibody used was FITC-conjugated goat anti-rabbit IgG (H+L) at 1/200 dilution for 30min at 4℃. Control antibody (green line) was Rabbit IgG (1μg/1*106 cells) used under the same conditions. Acquisition of >10,000 events was performed.

Human Fatty acid synthase(FASN) ELISA kit (CSB-EL008435HU)

驗(yàn)證數(shù)據(jù)

CSB-EL008435HU 標(biāo)準(zhǔn)曲線(xiàn)

貨號(hào):CSB-EL008435HU

規(guī)格:96T/48T

靈敏度:0.39 ng/mL

檢測(cè)范圍:1.56 ng/mL-100 ng/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

FAS Antibodies

FAS for Homo sapiens (Human)

FAS Proteins

FAS Proteins for Mus musculus (Mouse)

FAS Proteins for Homo sapiens (Human)

FAS Proteins for Bos taurus (Bovine)

FAS Proteins for Sus scrofa (Pig)

FAS Proteins for Rattus norvegicus (Rat)

FAS Proteins for Macaca nemestrina (Pig-tailed macaque)

FAS Proteins for Macaca mulatta (Rhesus macaque)

FAS Proteins for Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys)

FAS Proteins for Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)

FAS ELISA Kit

FAS ELISA Kit for Homo sapiens (Human)

FAS ELISA Kit for Rattus norvegicus (Rat)

FAS ELISA Kit for Mus musculus (Mouse)