GPR65
GPR65，全稱G蛋白偶聯(lián)受體65，也被稱為TDAG8，是一種與鞘糖脂精神胺相關(guān)的蛋白質(zhì)。它主要在T淋巴細(xì)胞、B淋巴細(xì)胞以及巨噬細(xì)胞等免疫細(xì)胞中表達(dá)。GPR65能夠感知細(xì)胞外pH值的變化，并在酸性環(huán)境下被激活，進(jìn)而參與多種生理和病理過程。研究表明，GPR65的激活可以抑制炎癥反應(yīng)，減輕疼痛，甚至抑制腫瘤生長(zhǎng)。因此，GPR65被認(rèn)為是多種疾病治療的潛在靶點(diǎn)。目前，已有研究人員開發(fā)了針對(duì)GPR65的激動(dòng)劑和拮抗劑，并正在探索其在治療炎癥性疾病、神經(jīng)性疼痛和腫瘤等方面的應(yīng)用。
熱銷產(chǎn)品
Recombinant Human Psychosine receptor (GPR65) (CSB-CF810304HU)
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
驗(yàn)證數(shù)據(jù)
The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using CSB-PA548371(GPR65 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ×200)
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA548371(GPR65 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ×200)
GPR65 Antibodies
GPR65 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA732036 | GPR65 Antibody | Human | ELISA,IHC |
| CSB-PA548371 | GPR65 Antibody | Human | ELISA,IHC |
GPR65 Proteins
GPR65 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP736801MO1 CSB-EP736801MO1 CSB-BP736801MO1 CSB-MP736801MO1 CSB-EP736801MO1-B |
Recombinant Mouse Psychosine receptor (Gpr65), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF736801MO | Recombinant Mouse Psychosine receptor (Gpr65) | in vitro E.coli expression system |
GPR65 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP810304HU1 CSB-EP810304HU1 CSB-BP810304HU1 CSB-MP810304HU1 CSB-EP810304HU1-B |
Recombinant Human Psychosine receptor (GPR65), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF810304HU | Recombinant Human Psychosine receptor (GPR65) | in vitro E.coli expression system |
| CSB-MP810304HU | Recombinant Human Psychosine receptor (GPR65)-VLPs | Mammalian cell |
