GYPA
血型糖蛋白A（GYPA）是一種高度糖基化的紅細胞表面蛋白，也被稱為CD235a或Gypa。它是紅細胞膜上主要的唾液酸糖蛋白，與血型糖蛋白B（GYPB）共同決定MNS血型系統(tǒng)的抗原特異性。GYPA在紅細胞上的數(shù)量高達10^6個，對維持紅細胞的形態(tài)和穩(wěn)定性至關(guān)重要。此外，GYPA還參與SLC4A1的功能調(diào)節(jié)，對SLC4A1的高活性表達具有促進作用。GYPA與多種疾病相關(guān)，包括遺傳性球形細胞增多癥和先天性紅細胞生成障礙性貧血等。在藥物研發(fā)方面，GYPA已成為治療貧血和輸血相關(guān)疾病的潛在靶點。目前，已有針對GYPA的單克隆抗體藥物進入臨床試驗階段，旨在提高輸血安全性和治療效果。
熱銷產(chǎn)品
GYPA Recombinant Monoclonal Antibody (CSB-RA257220A0HU)
驗證數(shù)據(jù)
Overlay Peak curve showing K562 cells surface stained with CSB-RA257220A0HU (red line) at 1:50. Then 10% normal goat serum to block non-specific protein-protein interactions followed by the antibody (1μg/1*106cells) for 45min at 4℃. The secondary antibody used was FITC-conjugated Goat Anti-rabbit IgG(H+L) at 1:200 dilution for 35min at 4℃.Control antibody (green line) was rabbit IgG (1μg/1*106cells) used under the same conditions. Acquisition of >10,000 events was performed.
GYPA Antibodies
GYPA for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA010074DD01HU | GYPA Antibody, Biotin conjugated | Human | ELISA |
| CSB-PA010074DB01HU | GYPA Antibody, HRP conjugated | Human | ELISA |
| CSB-PA010074GA01HU | GYPA Antibody | Human | ELISA,WB,IHC |
| CSB-PA010074DA01HU | GYPA Antibody | Human | ELISA |
| CSB-PA006301 | GYPA Antibody | Human | WB, ELISA |
| CSB-RA257220A0HU | GYPA Recombinant Monoclonal Antibody | Human | ELISA, FC |
GYPA Proteins
GYPA Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP010074MO1 CSB-EP010074MO1 CSB-BP010074MO1 CSB-MP010074MO1 CSB-EP010074MO1-B |
Recombinant Mouse Glycophorin-A (Gypa), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF010074MO | Recombinant Mouse Glycophorin-A (Gypa) | in vitro E.coli expression system |
GYPA Proteins for Canis familiaris (Dog) (Canis lupus familiaris)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP010074DO1 CSB-EP010074DO1 CSB-BP010074DO1 CSB-MP010074DO1 CSB-EP010074DO1-B |
Recombinant Dog Glycophorin-A (GYPA), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF010074DO | Recombinant Dog Glycophorin-A (GYPA) | in vitro E.coli expression system |
GYPA Proteins for Sus scrofa (Pig)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP010074PI1 CSB-EP010074PI1 CSB-BP010074PI1 CSB-MP010074PI1 CSB-EP010074PI1-B |
Recombinant Pig Glycophorin-A (GYPA), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF010074PI | Recombinant Pig Glycophorin-A (GYPA) | in vitro E.coli expression system |
GYPA Proteins for Macaca fuscata fuscata (Japanese macaque)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP010074MMX1 CSB-EP010074MMX1 CSB-BP010074MMX1 CSB-MP010074MMX1 CSB-EP010074MMX1-B |
Recombinant Macaca fuscata fuscata Glycophorin-A (GYPA), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF010074MMX | Recombinant Macaca fuscata fuscata Glycophorin-A (GYPA) | in vitro E.coli expression system |
GYPA Proteins for Pan troglodytes (Chimpanzee)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP634690EQV CSB-EP634690EQV CSB-BP634690EQV CSB-MP634690EQV CSB-EP634690EQV-B |
Recombinant Pan troglodytes Glycophorin-A (GYPA), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
