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IL2RG

IL2RG,即白介素2受體γ鏈,別名CD132。IL2RG是多種細(xì)胞因子受體的組成部分,包括IL-2、IL-4、IL-7、IL-9、IL-15和IL-21受體,被稱(chēng)為受體共同γ鏈。IL2RG與特定跨膜亞基形成異聚復(fù)合物,激活Janus激酶JAK1和JAK3,從而傳遞細(xì)胞因子的信號(hào)。IL2RG對(duì)于淋巴細(xì)胞的發(fā)育和功能至關(guān)重要,其基因突變可導(dǎo)致X連鎖嚴(yán)重聯(lián)合免疫缺陷(XSCID),表現(xiàn)為T(mén)細(xì)胞和NK細(xì)胞計(jì)數(shù)顯著下降,B細(xì)胞功能異常。

熱銷(xiāo)產(chǎn)品

Recombinant Human Cytokine receptor common subunit gamma(IL2RG),partial (Active) (CSB-MP011651HU4)

驗(yàn)證數(shù)據(jù)

CSB-MP011651HU4

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

CSB-MP011651HU4

Activity
Measured by its binding ability in a functional ELISA. Immobilized Human IL2RG at 2 μg/ml can bind Anti-IL2RG recombinant antibody (CSB-RA011651MA1HU). The EC50 is 12.19-13.63 ng/mL.

IL2RG Antibody (CSB-PA011651EA01HU)

驗(yàn)證數(shù)據(jù)

CSB-PA011651EA01HU

Western blot
All lanes: IL2RG antibody at 12µg/ml
Lane 1: Jurkat whole cell lysate
Lane 2: K562 whole cell lysate
Lane 3: HL60 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 43, 21 kDa
Observed band size: 43 kDa

CSB-PA011651EA01HU

Immunohistochemistry of paraffin-embedded human spleen tissue using CSB-PA011651EA01HU at dilution of 1:100

Human Cytokine receptor common subunit gamma(IL2RG) ELISA kit (CSB-EL011651HU)

驗(yàn)證數(shù)據(jù)

CSB-EL011651HU 標(biāo)準(zhǔn)曲線

貨號(hào):CSB-EL011651HU

規(guī)格:96T/48T

靈敏度:0.078 ng/mL

檢測(cè)范圍:0.312 ng/mL-20 ng/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

IL2RG Antibodies

IL2RG for Homo sapiens (Human)

IL2RG Proteins

IL2RG Proteins for Homo sapiens (Human)

IL2RG Proteins for Canis familiaris (Dog) (Canis lupus familiaris)

IL2RG Proteins for Mus musculus (Mouse)

IL2RG Proteins for Bos taurus (Bovine)

IL2RG ELISA Kit

IL2RG ELISA Kit for Homo sapiens (Human)