MME
MME，全名為膜金屬內(nèi)肽酶（membrane metalloendopeptidase），也被稱為中性內(nèi)肽酶、腦啡肽酶、神經(jīng)肽酶等。MME蛋白在細(xì)胞表面表達(dá)，主要功能是降解多肽，包括阿片肽、緩激肽、P物質(zhì)和神經(jīng)降壓素肽等。它在神經(jīng)遞質(zhì)和激素的降解中起關(guān)鍵作用，與多種生理過程相關(guān)。MME蛋白與阿爾茨海默病、多發(fā)性硬化癥、癌癥等多種疾病有關(guān)，因此成為藥物研發(fā)的熱點(diǎn)靶點(diǎn)。目前，針對(duì)MME蛋白的藥物研發(fā)主要集中在開發(fā)能夠抑制其活性的藥物，以治療相關(guān)疾病。
熱銷產(chǎn)品
Recombinant Human Neprilysin (MME), partial (CSB-YP014653HU)
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Based on the SEQUEST from database of Yeast host and target protein, the LC-MS/MS Analysis result of CSB-YP014653HU could indicate that this peptide derived from Yeast-expressed Homo sapiens (Human) MME.
Based on the SEQUEST from database of Yeast host and target protein, the LC-MS/MS Analysis result of CSB-YP014653HU could indicate that this peptide derived from Yeast-expressed Homo sapiens (Human) MME.
MME Recombinant Monoclonal Antibody (CSB-RA940661A0HU)
驗(yàn)證數(shù)據(jù)
Western Blot
Positive WB detected in: U251 whole cell lysate
All lanes: MME antibody at 1:1500
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 86 kDa
Observed band size: 100 kDa
MME Antibodies
MME for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA014653GA01HU | MME Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA985136 | MME Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA005556 | MME Antibody | Human,Mouse,Rat | WB, ELISA |
| CSB-PA086078 | MME Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA927708 | MME Antibody | Human,Mouse,Rat | ELISA,IHC |
| CSB-PA897259 | MME Antibody | Human,Mouse,Rat | IHC,ELISA |
| CSB-PA014653LA01HU | MME Antibody | Human | ELISA, IHC |
| CSB-PA014653LB01HU | MME Antibody, HRP conjugated | Human | ELISA |
| CSB-PA014653LC01HU | MME Antibody, FITC conjugated | Human | |
| CSB-PA014653LD01HU | MME Antibody, Biotin conjugated | Human | ELISA |
| CSB-PA014653LA11HU | MME Antibody | Human | ELISA, IHC, IF |
| CSB-PA014653LB11HU | MME Antibody, HRP conjugated | Human | ELISA |
| CSB-PA014653LC11HU | MME Antibody, FITC conjugated | Human | |
| CSB-PA014653LD11HU | MME Antibody, Biotin conjugated | Human | ELISA |
| CSB-RA940661A0HU | MME Recombinant Monoclonal Antibody | Human | ELISA, WB |
| CSB-RA187479A0HU | MME Recombinant Monoclonal Antibody | Human | ELISA, IHC |
MME for H, M, R
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-MA000230 | MME Monoclonal Antibody | Human,Mouse,Rat | ELISA,IHC |
MME Proteins
MME Proteins for Sus scrofa (Pig)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP014653PI CSB-EP014653PI CSB-BP014653PI CSB-MP014653PI CSB-EP014653PI-B |
Recombinant Pig Neprilysin (MME) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
MME Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP014653HU | Recombinant Human Neprilysin (MME), partial | Yeast |
| CSB-EP014653HU CSB-BP014653HU CSB-MP014653HU CSB-EP014653HU-B |
Recombinant Human Neprilysin (MME), partial | E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
MME Proteins for Oryctolagus cuniculus (Rabbit)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP014653RB1 CSB-EP014653RB1 CSB-BP014653RB1 CSB-MP014653RB1 CSB-EP014653RB1-B |
Recombinant Rabbit Neprilysin (MME), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF014653RB | Recombinant Rabbit Neprilysin (MME) | in vitro E.coli expression system |
MME Proteins for Rattus norvegicus (Rat)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP362251RA CSB-EP362251RA CSB-BP362251RA CSB-MP362251RA CSB-EP362251RA-B |
Recombinant Rat Neprilysin (Mme), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
MME Proteins for Pongo abelii (Sumatran orangutan)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP722446PYX CSB-EP722446PYX CSB-BP722446PYX CSB-MP722446PYX CSB-EP722446PYX-B |
Recombinant Pongo abelii Neprilysin (MME), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
MME Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP723409MO CSB-EP723409MO CSB-BP723409MO CSB-MP723409MO CSB-EP723409MO-B |
Recombinant Mouse Neprilysin (Mme), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
MME ELISA Kit
MME ELISA Kit for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-EL014653MO | Mouse Neprilysin(MME) ELISA kit | serum, plasma,tissue homogenates | 0.039 ng/mL |
MME ELISA Kit for Rattus norvegicus (Rat)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-EL014653RA | Rat Neprilysin(MME) ELISA kit | serum, plasma, tissue homogenates | 11.75 pg/mL |
MME ELISA Kit for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E13347h | Human Neprilysin(NEP) ELISA Kit | serum, plasma, tissue homogenates | 19.5 pg/mL |
