NINJ1
NINJ1，全稱為Nerve Injury-Induced Protein 1，是一種在神經(jīng)損傷后誘導(dǎo)表達(dá)的細(xì)胞表面蛋白，最初在神經(jīng)系統(tǒng)中發(fā)現(xiàn)。它是一種細(xì)胞間粘附分子，參與多種生物學(xué)過(guò)程，尤其是在細(xì)胞損傷和修復(fù)、炎癥反應(yīng)以及細(xì)胞死亡中起著重要作用。NINJ1在多種疾病中發(fā)揮重要作用。作為神經(jīng)損傷誘導(dǎo)蛋白，NINJ1在神經(jīng)再生和修復(fù)中起到關(guān)鍵作用，通過(guò)上調(diào)表達(dá)促進(jìn)軸突生長(zhǎng)和神經(jīng)功能恢復(fù)。在炎癥性疾病中，NINJ1的調(diào)控作用使其成為潛在的治療靶點(diǎn)，通過(guò)抑制NINJ1可以減少免疫細(xì)胞的過(guò)度募集和激活，從而減輕炎癥反應(yīng)。在某些腫瘤中，NINJ1的表達(dá)可能影響腫瘤細(xì)胞的粘附和遷移，進(jìn)而影響腫瘤的侵襲和轉(zhuǎn)移能力。近年來(lái)，研究發(fā)現(xiàn)NINJ1抗體可以阻斷其寡聚化，從而預(yù)防細(xì)胞膜破裂，為減少組織損傷提供了新思路，特別是在肝細(xì)胞死亡引發(fā)的疾病中。這一發(fā)現(xiàn)為開(kāi)發(fā)新的抗炎治療方法提供了重要的理論基礎(chǔ)和潛在的臨床應(yīng)用價(jià)值。
熱銷產(chǎn)品
Recombinant Human Ninjurin-1 (NINJ1) (CSB-CF856441HU)
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
NINJ1 Antibody (CSB-PA856441LA01HU)
驗(yàn)證數(shù)據(jù)
Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA856441LA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human lung cancer using CSB-PA856441LA01HU at dilution of 1:100
Immunofluorescent analysis of HepG2 cells using CSB-PA856441LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
Immunofluorescent analysis of A549 cells using CSB-PA856441LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
Human Ninjurin-1(NINJ1) ELISA kit (CSB-EL015808HU)
驗(yàn)證數(shù)據(jù)
貨號(hào)：CSB-EL015808HU
規(guī)格：96T/48T
靈敏度：6.25 pg/mL
檢測(cè)范圍：25 pg/mL-1600 pg/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
NINJ1 Antibodies
NINJ1 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA856441LA01HU | NINJ1 Antibody | Human | ELISA, IHC, IF |
| CSB-PA856441LB01HU | NINJ1 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA856441LC01HU | NINJ1 Antibody, FITC conjugated | Human | |
| CSB-PA856441LD01HU | NINJ1 Antibody, Biotin conjugated | Human | ELISA |
NINJ1 Proteins
NINJ1 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP856441HU1 CSB-EP856441HU1 CSB-BP856441HU1 CSB-MP856441HU1 CSB-EP856441HU1-B |
Recombinant Human Ninjurin-1 (NINJ1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF856441HU | Recombinant Human Ninjurin-1 (NINJ1) | in vitro E.coli expression system |
| CSB-MP856441HU | Recombinant Human Ninjurin-1 (NINJ1)-VLPs | Mammalian cell |
NINJ1 ELISA Kit
NINJ1 ELISA Kit for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-EL015808HU | Human Ninjurin-1(NINJ1) ELISA kit | serum, plasma, tissue homogenates, cell lysates | 6.25 pg/mL |
