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SDC1

SDC1,全稱為Syndecan-1,也被稱為CD138,是一種細(xì)胞表面蛋白聚糖。它在細(xì)胞通訊和信號傳導(dǎo)中發(fā)揮作用,參與多種細(xì)胞過程。Syndecan-1在多種組織中的表達(dá)譜強(qiáng)調(diào)了它在不同生理環(huán)境中的重要性。在腫瘤發(fā)生發(fā)展中,Syndecan-1與細(xì)胞增殖、凋亡、血管生成、遷移侵襲和耐藥等過程有關(guān)。例如,在乳腺癌中,Syndecan-1的表達(dá)與腫瘤的侵襲和轉(zhuǎn)移相關(guān)。因此,Syndecan-1已成為腫瘤診斷和治療的重要靶點(diǎn)。目前,針對Syndecan-1的抑制劑正在研發(fā)中,有望為腫瘤治療提供新的策略。

熱銷產(chǎn)品

Recombinant Human Syndecan-1 (SDC1), partial (CSB-EP020888HU)

驗(yàn)證數(shù)據(jù)

CSB-EP020888HU

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

SDC1 Recombinant Monoclonal Antibody (CSB-RA020888MA1HU)

驗(yàn)證數(shù)據(jù)

CSB-RA020888MA1HU

IHC image of CSB-RA020888MA1HU diluted at 1:300 and staining in paraffin-embedded human skin tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-Human IgG labeled by HRP and visualized using 0.05% DAB.

CSB-RA020888MA1HU

Immunofluorescence staining of Hela cell with CSB-RA020888MA1HU at 1:80, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4C. The secondary antibody was FITC-conjugated AffiniPure Goat Anti-Human IgG(H+L).

SDC1 Antibodies

SDC1 for Homo sapiens (Human)

SDC1 for Rattus norvegicus (Rat)

SDC1 Proteins

SDC1 Proteins for Homo sapiens (Human)

SDC1 Proteins for Mus musculus (Mouse)

SDC1 Proteins for Rattus norvegicus (Rat)

SDC1 Proteins for Mesocricetus auratus (Golden hamster)

SDC1 Proteins for Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)

SDC1 Proteins for Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

SDC1 Proteins for Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)

SDC1 ELISA Kit

SDC1 ELISA Kit for Homo sapiens (Human)

SDC1 ELISA Kit for Mus musculus (Mouse)

SDC1 ELISA Kit for Rattus norvegicus (Rat)