SLC10A2
SLC10A2，即溶質(zhì)載體家族10成員2，別名ASBT、IBAT、ISBT。SLC10A2主要在回腸腸細胞頂端膜表達，負責將膽汁酸從腸腔內(nèi)吸收到腸細胞中，是膽汁酸腸肝循環(huán)的關(guān)鍵轉(zhuǎn)運蛋白。
SLC10A2參與膽汁酸和膽汁鹽的轉(zhuǎn)運，位于頂端質(zhì)膜和細胞核中，是蛋白酶體復(fù)合物的一部分。SLC10A2對于維持膽汁酸的腸肝循環(huán)、膽固醇穩(wěn)態(tài)以及腸道運動具有重要作用。功能異?？赡軐?dǎo)致與膽汁酸腸肝循環(huán)和膽固醇穩(wěn)態(tài)失調(diào)相關(guān)的疾病，如腹瀉、膽結(jié)石、炎癥性腸病、便秘、Alagille綜合征、家族性高甘油三酯血癥、先天性慢性腹瀉、腸易激綜合征、非酒精性脂肪性肝炎（NASH）等。
熱銷產(chǎn)品
SLC10A2 Antibody (CSB-PA622519LA01HU)
驗證數(shù)據(jù)
Immunohistochemistry of paraffin-embedded human endometrial cancer using CSB-PA622519LA01HU at dilution of 1:100
Immunofluorescent analysis of A431 cells using CSB-PA622519LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
SLC10A2 Antibodies
SLC10A2 for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA622519LA01HU | SLC10A2 Antibody | Human | ELISA, IHC, IF |
| CSB-PA622519LB01HU | SLC10A2 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA622519LC01HU | SLC10A2 Antibody, FITC conjugated | Human | |
| CSB-PA622519LD01HU | SLC10A2 Antibody, Biotin conjugated | Human | ELISA |
| CSB-PA843819 | SLC10A2 Antibody | Human, Mouse | ELISA, WB |
SLC10A2 Proteins
SLC10A2 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP622519HU CSB-EP622519HU CSB-BP622519HU CSB-MP622519HU CSB-EP622519HU-B |
Recombinant Human Ileal sodium/bile acid cotransporter (SLC10A2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-MP622519HU(A4) | Recombinant Human Ileal sodium/bile acid cotransporter (SLC10A2)-VLPs | Mammalian cell |
