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SOCS4

Suppressor of cytokine signaling 4 is a protein in humans that is encoded by SOCS4 gene. SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. Substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Inhibits EGF signaling by mediating the degradation of the Tyr-phosphorylated EGF receptor/EGFR.

SOCS4 Antibodies

SOCS4 for Homo sapiens (Human)

SOCS4 Proteins

SOCS4 Proteins for Pongo abelii (Sumatran orangutan)

SOCS4 Proteins for Homo sapiens (Human)

SOCS4 Proteins for Mus musculus (Mouse)

SOCS4 Proteins for Bos taurus (Bovine)