TGFB3
轉(zhuǎn)化生長(zhǎng)因子-β3（TGF-β3）是調(diào)控胚胎發(fā)育和組織穩(wěn)態(tài)的重要蛋白，在哺乳動(dòng)物中也被簡(jiǎn)稱為TGFB3。該蛋白屬于轉(zhuǎn)化生長(zhǎng)因子超家族成員，與TGF-β1、TGF-β2具有相似結(jié)構(gòu)但獨(dú)特功能，尤其在心臟形態(tài)建成和腭板融合過(guò)程中起關(guān)鍵作用。TGFB3通過(guò)激活特定胞內(nèi)分子網(wǎng)絡(luò)，影響細(xì)胞增殖、分化及胞外基質(zhì)沉積，異常表達(dá)可能引發(fā)先天性心臟病、腭裂等發(fā)育缺陷，并與肺纖維化、腫瘤轉(zhuǎn)移等病理過(guò)程相關(guān)。近年有學(xué)者發(fā)現(xiàn)該蛋白在調(diào)控免疫微環(huán)境和抑制過(guò)度瘢痕形成方面具有潛力，相關(guān)抗體藥物如GC1008已進(jìn)入臨床試驗(yàn)，用于特發(fā)性肺纖維化等疾病的干預(yù)。不過(guò)由于TGF-β家族成員功能的高度復(fù)雜性，針對(duì)TGF-β3的特異性靶向治療仍需突破多重技術(shù)瓶頸。
熱銷產(chǎn)品
Recombinant Human Transforming growth factor beta-3 (TGFB3), partial (CSB-EP023449HU1)
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
TGFB3 Antibody (CSB-PA023449LA01HU)
驗(yàn)證數(shù)據(jù)
Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA023449LA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA023449LA01HU at dilution of 1:100
Human Transforming Growth factor β3,TGF-β3 ELISA kit (CSB-E13738h)
驗(yàn)證數(shù)據(jù)
貨號(hào)：CSB-E13738h
規(guī)格：96T/48T
靈敏度：3.9 pg/mL
檢測(cè)范圍：15.6 pg/mL-1000 pg/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
TGFB3 Antibodies
TGFB3 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA023449GA01HU | TGFB3 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA17749C0Rb | TGFB3 Antibody, FITC conjugated | Human | |
| CSB-PA17749B0Rb | TGFB3 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA17749D0Rb | TGFB3 Antibody, Biotin conjugated | Human | ELISA |
| CSB-PA217147 | TGFB3 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA004283 | TGFB3 Antibody | Human,Mouse,Rat,Monkey | WB, IHC, ELISA |
| CSB-PA023449LA01HU | TGFB3 Antibody | Human | ELISA, IHC |
| CSB-PA023449LD01HU | TGFB3 Antibody, Biotin conjugated | Human | ELISA |
| CSB-PA023449LC01HU | TGFB3 Antibody, FITC conjugated | Human | |
| CSB-PA023449LB01HU | TGFB3 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA17749A0Rb | TGFB3 Antibody | Human | ELISA, IHC |
TGFB3 Proteins
TGFB3 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP023449HU CSB-BP023449HU CSB-MP023449HU CSB-EP023449HU-B |
Recombinant Human Transforming growth factor beta-3 (TGFB3), partial | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP023449HU1 | Recombinant Human Transforming growth factor beta-3 (TGFB3), partial | E.coli |
| CSB-EP023449HU | Recombinant Human Transforming growth factor beta-3 (TGFB3), partial | E.coli |
| CSB-AP004051HU | Recombinant Human Transforming growth factor beta-3 (TGFB3),Partial (Active) | Mammalian cell |
| CSB-MP023449HU-WD | Recombinant Human Transforming growth factor beta-3 proprotein (TGFB3)，Partial (Active) | Mammalian cell |
TGFB3 Proteins for Gallus gallus (Chicken)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP023449CH CSB-EP023449CH CSB-BP023449CH CSB-MP023449CH CSB-EP023449CH-B |
Recombinant Chicken Transforming growth factor beta-3 (TGFB3) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TGFB3 Proteins for Sus scrofa (Pig)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP023449PI CSB-EP023449PI CSB-BP023449PI CSB-MP023449PI CSB-EP023449PI-B |
Recombinant Pig Transforming growth factor beta-3 (TGFB3) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TGFB3 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP023449MO CSB-EP023449MO CSB-BP023449MO CSB-MP023449MO CSB-EP023449MO-B |
Recombinant Mouse Transforming growth factor beta-3 (Tgfb3), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TGFB3 ELISA Kit
TGFB3 ELISA Kit for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E13738h | Human Transforming Growth factor β3,TGF-β3 ELISA kit | serum, plasma, cell culture supernates | 3.9 pg/mL |
TGFB3 ELISA Kit for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E12862m | Mouse Transforming Growth factor β3,TGF-β3 ELISA kit | serum, plasma, cell culture supernates, tissue homogenates | 31.25 pg/mL |
