TNFRSF13B

TNFRSF13B，即腫瘤壞死因子受體超家族成員13B，別名B細胞活化因子（BAFF）、TALL-1、CD267、TACI配體等。它是一種主要由單核細胞、樹突狀細胞及T細胞產(chǎn)生的細胞因子，屬于腫瘤壞死因子超家族成員。TNFRSF13B在免疫應答中起重要作用，尤其是促進B細胞的成熟和分化，并與自身免疫密切相關。其作用機制涉及與其受體TACI、BCMA和BAFFR等結合，激活下游的信號傳導途徑，如NF-κB、JAK/STAT等，進而影響B(tài)細胞的存活、增殖和分化。TNFRSF13B在生物學上的意義非常廣泛，它參與了多種生理和病理過程的調(diào)節(jié)。在正常生理條件下，TNFRSF13B對于維持B細胞穩(wěn)態(tài)和抗體產(chǎn)生至關重要。在病理條件下，TNFRSF13B的異常表達或功能失調(diào)與多種自身免疫性疾病的發(fā)生發(fā)展有關，如系統(tǒng)性紅斑狼瘡、類風濕關節(jié)炎等。此外，TNFRSF13B還可能參與某些B細胞淋巴瘤的發(fā)展。因此，TNFRSF13B是免疫學研究和相關疾病治療中的一個潛在靶點。

熱銷產(chǎn)品

Recombinant Human Tumor necrosis factor receptor superfamily member 13B protein (TNFRSF13B), partial (Active) (CSB-AP002301HU)

驗證數(shù)據(jù)

TNFRSF13B Antibody (CSB-PA006292)

驗證數(shù)據(jù)

Western Blot analysis of 3T3 cells using CD267 Polyclonal Antibody

Western Blot analysis of NIH-3T3 cells using CD267 Polyclonal Antibody

TNFRSF13B Antibody

TNFRSF13B Protein

TNFRSF13B ELISA Kit

TNFRSF13B Antibodies

TNFRSF13B for Homo sapiens (Human)

產(chǎn)品貨號	產(chǎn)品名稱	種屬反應性	應用類型
CSB-PA023971GA01HU	TNFRSF13B Antibody	Human	ELISA,WB
CSB-PA023971DSR2HU	TNFRSF13B Antibody	Human	ELISA, IHC
CSB-PA006292	TNFRSF13B Antibody	Human	WB, ELISA

TNFRSF13B Proteins

TNFRSF13B Proteins for Homo sapiens (Human)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP023971HU1 CSB-EP023971HU1 CSB-BP023971HU1 CSB-EP023971HU1-B	Recombinant Human Tumor necrosis factor receptor superfamily member 13B (TNFRSF13B), partial	Yeast E.coli Baculovirus In Vivo Biotinylation in E.coli
CSB-AP002301HU	Recombinant Human Tumor necrosis factor receptor superfamily member 13B protein (TNFRSF13B), partial (Active)	E.Coli
CSB-CF023971HU	Recombinant Human Tumor necrosis factor receptor superfamily member 13B (TNFRSF13B)	in vitro E.coli expression system

TNFRSF13B Proteins for Mus musculus (Mouse)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP863678MO CSB-EP863678MO CSB-BP863678MO CSB-MP863678MO CSB-EP863678MO-B	Recombinant Mouse Tumor necrosis factor receptor superfamily member 13B (Tnfrsf13b), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli