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中文名稱:人載脂蛋白A4(Apo-A4)酶聯(lián)免疫試劑盒
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貨號:CSB-E15088h
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規(guī)格:96T/48T
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價格:¥3600/¥2500
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其他:
產(chǎn)品詳情
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產(chǎn)品描述:人載脂蛋白A4(Apo-A4)酶聯(lián)免疫試劑盒(CSB-E15088h)為雙抗夾心法ELISA試劑盒,定量檢測血清、血漿、組織勻漿樣本中的APOA4含量。APOA4 即載脂蛋白 A4,在脂質(zhì)代謝等方面發(fā)揮重要作用。研究發(fā)現(xiàn)它能促進膽固醇逆向轉(zhuǎn)運、調(diào)節(jié)脂蛋白代謝。其作為靶點,在治療高脂血癥、動脈粥樣硬化等疾病上有潛在價值,通過調(diào)控相關(guān)代謝機制有望開發(fā)新型治療方案。試劑盒檢測范圍為0.041 ng/ml- 30 ng/ml,靈敏度為0.041 ng/ml。適用于心血管疾病、脂代謝異常及相關(guān)病理機制的體外研究??蓱?yīng)用于基礎(chǔ)科研中Apo - A4表達水平的動態(tài)監(jiān)測,如動脈粥樣硬化模型研究、肥胖或糖尿病相關(guān)代謝紊亂的分子機制探索,以及藥物干預(yù)對脂蛋白代謝影響的體外評估。本品僅用于科研,不用于臨床診斷,產(chǎn)品具體參數(shù)及操作步驟詳見產(chǎn)品說明書。
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縮寫:APOA4
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Uniprot No.:
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種屬:Homo sapiens (Human)
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樣本類型:serum, plasma, tissue homogenates
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檢測范圍:0.041 ng/ml- 30 ng/ml
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靈敏度:0.041 ng/ml
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反應(yīng)時間:1-5h
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樣本體積:50-100ul
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檢測波長:450 nm
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研究領(lǐng)域:Cancer
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測定原理:quantitative
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測定方法:Sandwich
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精密度:
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線性度:
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回收率:
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標準曲線:
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數(shù)據(jù)處理:
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貨期:3-5 working days
引用文獻
- Depression Augments Plasma APOA4 without Changes of Plasma Lipids and Glucose in Female Adolescents Carrying G Allele of APOA4 rs5104 QW Guo,Journal of Molecular Neuroscience,2021
- Screening and identification of potential protein biomarkers for evaluating the efficacy of intensive therapy in pulmonary tuberculosis Ting-TingJiang.et al,Biochemical and Biophysical Research Communications,2018
靶點詳情
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最新研究進展:APOA4是一種主要存在于高密度脂蛋白(HDL)中的蛋白質(zhì)。最新研究表明,APOA4在人體內(nèi)具有抗炎、抗氧化、調(diào)節(jié)脂質(zhì)代謝和血糖代謝等多種生物學(xué)功能。APOA4的異常表達與多種代謝性疾病,如肥胖、2型糖尿病和心血管疾病等的發(fā)生密切相關(guān)。
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功能:May have a role in chylomicrons and VLDL secretion and catabolism. Required for efficient activation of lipoprotein lipase by ApoC-II; potent activator of LCAT. Apoa-IV is a major component of HDL and chylomicrons.
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亞細胞定位:Secreted.
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蛋白家族:Apolipoprotein A1/A4/E family
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組織特異性:Synthesized primarily in the intestine and secreted in plasma.
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數(shù)據(jù)庫鏈接:
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