Human voltage-gated potassium channel antibody (VGKC-ab) ELISA Kit
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中文名稱:人電壓門控鉀通道抗體(VGKC-ab)抗體酶聯(lián)免疫試劑盒
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貨號:CSB-E13512h
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規(guī)格:96T/48T
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價格:¥3900/¥2500
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其他:
產(chǎn)品詳情
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產(chǎn)品描述:人電壓門控鉀通道抗體(VGKC-ab)抗體酶聯(lián)免疫試劑盒(CSB-E13512h)為間接法ELISA試劑盒,定性檢測血清樣本中的VGKC Ab含量。VGKC Ab即電壓門控鉀離子通道抗體,它與多種神經(jīng)免疫性疾病相關(guān)。其研究機(jī)制主要是該抗體與電壓門控鉀離子通道結(jié)合后,會影響離子通道功能,干擾神經(jīng)細(xì)胞膜電位的正常變化,進(jìn)而影響神經(jīng)信號傳導(dǎo),引發(fā)相關(guān)臨床癥狀。該產(chǎn)品專為科研設(shè)計,可用于探索VGKC - ab在自身免疫性疾病動物模型中的表達(dá)特征、評估抗體水平與神經(jīng)功能障礙的相關(guān)性,或作為神經(jīng)免疫病理機(jī)制研究的輔助工具,為抗體介導(dǎo)的離子通道功能研究提供實(shí)驗(yàn)依據(jù)。適用于實(shí)驗(yàn)室對血清樣本的批量篩查及基礎(chǔ)研究中的生物標(biāo)志物分析。本品僅用于科研,不用于臨床診斷,產(chǎn)品具體參數(shù)及操作步驟詳見產(chǎn)品說明書。
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縮寫:VGKC Ab
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種屬:Homo sapiens (Human)
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樣本類型:serum
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檢測范圍:Request Information
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靈敏度:Request Information
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反應(yīng)時間:1-5h
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樣本體積:50-100ul
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檢測波長:450 nm
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研究領(lǐng)域:Others
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測定原理:qualitative
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測定方法:Indirect
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精密度:
Intra-assay Precision (Precision within an assay): CV%<15%
Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision (Precision between assays): CV%<15%
Three samples of known concentration were tested in twenty assays to assess.
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標(biāo)準(zhǔn)曲線:
Test parameter
specification
test result
Positive control
>0.8
1.156
Negative control
<0.2
0.123
Positive rate
10,Positive
100%
Negative rate
10,Negative
100%
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貨期:3-5 working days
引用文獻(xiàn)
- Immunotherapy by targeting of VGKC complex for seizure control and prevention of cognitive impairment in a mouse model of epilepsy Zhiliang Fan.et al,Molecular Medicine Reports,2018
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