Mouse anti-double stranded DNA antibody (IgG) ELISA Kit
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中文名稱:小鼠抗雙鏈DNA抗體/天然DNA抗體(IgG)酶聯(lián)免疫試劑盒
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貨號(hào):CSB-E11194m
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規(guī)格:96T/48T
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價(jià)格:¥3200/¥2500
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其他:
產(chǎn)品詳情
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產(chǎn)品描述:小鼠抗雙鏈DNA抗體/天然DNA抗體(IgG)酶聯(lián)免疫試劑盒(CSB-E11194m)為間接法 ELISA試劑盒,定性檢測(cè)血清樣本中的dsDNA Ab (IgG)含量。dsDNA Ab (IgG)即抗雙鏈DNA抗體(IgG型)。它是系統(tǒng)性紅斑狼瘡(SLE)的重要血清學(xué)標(biāo)志物,與疾病的發(fā)生發(fā)展密切相關(guān)。其研究機(jī)制主要是它能與雙鏈DNA結(jié)合形成免疫復(fù)合物,沉積在組織器官,激活補(bǔ)體系統(tǒng),進(jìn)而引發(fā)炎癥反應(yīng)損傷組織。本產(chǎn)品適用于科研實(shí)驗(yàn)中評(píng)估小鼠自身免疫疾病模型(如系統(tǒng)性紅斑狼瘡)的抗體動(dòng)態(tài)變化、病理機(jī)制研究或藥物干預(yù)效果分析,為探索抗dsDNA抗體在免疫異常反應(yīng)中的作用提供實(shí)驗(yàn)支持。本品僅用于科研,不用于臨床診斷,產(chǎn)品具體參數(shù)及操作步驟詳見產(chǎn)品說明書。
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縮寫:dsDNA Ab (IgG)
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種屬:Mus musculus (Mouse)
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樣本類型:serum
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檢測(cè)范圍:
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靈敏度:
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反應(yīng)時(shí)間:1-5h
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樣本體積:50-100ul
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檢測(cè)波長:450 nm
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研究領(lǐng)域:Others
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測(cè)定原理:qualitative
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測(cè)定方法:Indirect
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標(biāo)準(zhǔn)曲線:
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貨期:3-5 working days
引用文獻(xiàn)
- Microbiota‐Derived Inosine Suppresses Systemic Autoimmunity via Restriction of B Cell Differentiation and Migration L Gao, Y Zhang, Z Hu, S Chen, Q Wang,Advanced Science,2025
- Ginsenoside CK potentiates SIRT1 to alleviate lupus nephritis through compensating for XBP1-mediated endoplasmic reticulum stress in plasma cells Z Song, Y Li, S Xu, S Qian, W Xu, L Xu, F Tian,Journal of Pharmaceutical Analysis,2025
- MAPK4 inhibits the early aberrant activation of B cells in rheumatoid arthritis by promoting the IRF4-SHIP1 signaling pathway P Huang, G Yang, P Zhang, Y Zhu, Y Guan, J Sun,Cell Death & Disease,2025
- Dysregulation in keratinocytes drives systemic lupus erythematosus onset J Tian, L Shi, D Zhang, X Yao, M Zhao,Cellular & Molecular Immunology,2025
- SATB1 prevents immune cell infiltration by regulating chromatin organization and gene expression of a chemokine gene cluster in T cells B Wang, Q Bian,Communications Biology,2024
- TM9SF1 expression correlates with autoimmune disease activity and regulates antibody production through mTOR-dependent autophagy J Xiao, Z Zhao, F Zhou, J Xiong, Z Yang,BMC medicine,2024
- A rationally designed CD19 monoclonal antibody-triptolide conjugate for the treatment of systemic lupus erythematosus L Wang, H Yin, J Jiang, Q Li, C Gao, W Li,Acta Pharmaceutica Sinica B,2024
- MME and PTPRC: key renal biomarkers in lupus nephritis M Wen, M Hun, M Zhao, Q He,PeerJ,2024
- Hippo pathway and NLRP3-driven NETosis in macrophages: Mechanisms of viral pneumonia aggravation L Pan,Cell Death Discovery,2024
- Mesenchymal stem cells-derived extracellular vesicles ameliorate lupus nephritis by regulating T and B cell responses C Li,Stem cell research & therapy,2024
- Jieduquyuziyin prescription attenuates the side effect of prednisone through regulating gut microbiota when in the combination with prednisone treat MRL/lpr mice Z Zhu,Journal of Traditional and Complementary Medicine,2024
- Deletion of the Mitochondrial Membrane Protein Fam210b Is Associated with the Development of Systemic Lupus Erythematosus Y Xu,International Journal of Molecular Sciences,2024
- Podocyte SIRPα reduction aggravates lupus nephritis via promoting T cell inflammatory responses B Qian,Cell reports,2024
- Microplastics exposure induced and exacerbated the development of systemic lupus erythematosus in mice H Chen,The Science of the total environment,2023
- The phagocytosis dysfunction in lupus nephritis is related to monocyte/macrophage CPT1a Q Yuan,Immunology letters,2024
- Endogenous retrovirus promotes the aberrant T cell differentiation in systemic lupus erythematosus via RIG-I pathway R Patil,/,2024
- TIGIT-Fc fusion protein alleviates murine lupus nephritis through the regulation of SPI-B-PAX5-XBP1 axis-mediated B-cell differentiation J Zhao,Journal of autoimmunity,2023
- Blockade of OX40/OX40L signaling using anti-OX40L delays disease progression in murine lupus J Zhao,researchsquare,2023
- Gut microbiota mediated the effects of high relative humidity on lupus in female MRL/lpr mice C Wang,Advances in rheumatology,2023
- LncRNA IL21‐AS1 interacts with hnRNPU protein to promote IL21 overexpression and aberrant differentiation of Tfh cells in systemic lupus erythematosus L Liu,Clinical and translational medicine,2022
- Inhibition of CEBPB Attenuates Lupus Nephritis via Regulating Pim-1 Signaling. X Wang,Mediators of Inflammation,2022
- GDF-15: A Potential Biomarker and Therapeutic Target in Systemic Lupus Erythematosus WD Xu,Frontiers in immunology,2022
- Overexpression of FcγRIIB regulates downstream protein phosphorylation and suppresses B cell activation to ameliorate systemic lupus erythematosus L Sheng,International Journal of Molecular Medicine,2020
- MicroRNA-10a-3p mediates Th17/Treg cell balance and improves renal injury by inhibiting REG3A in lupus nephritis G You,International Immunopharmacology,2020
- Interleukin-25 is upregulated in patients with systemic lupus erythematosus and ameliorates murine lupus by inhibiting inflammatory cytokine production Li Y,International Immunopharmacology,2019
產(chǎn)品評(píng)價(jià)
樣品類型:血漿(抗凝劑)
樣品信息:小鼠
稀釋比:其他
產(chǎn)品評(píng)價(jià): 我用CSB-E11194m檢測(cè)正常及SLE模型小鼠血漿中IgG的表達(dá)情況,1:10稀釋后其OD值在0.19~0.649之間,測(cè)量的結(jié)果濃度較低。產(chǎn)品操作便捷,使用方便,說明書詳細(xì),但建議不同樣本要進(jìn)行預(yù)實(shí)驗(yàn)摸好濃度范圍再進(jìn)行大批量實(shí)驗(yàn)。
By 楊老師
樣品類型:血清
樣品信息:小鼠
稀釋比:其他 1:10
產(chǎn)品評(píng)價(jià): 我用CSB-E11194m試劑盒檢測(cè)了小鼠的dsDNA
By 邱老師
樣品類型:血漿(抗凝劑) 稀釋20倍
樣品信息:小鼠
稀釋比:其他 1:20
產(chǎn)品評(píng)價(jià): 我用CSB-11194m檢測(cè)小鼠血漿的自身抗體,這個(gè)elisa試劑盒的效果十分穩(wěn)定,周圍人也全是用的華美的試劑盒。以前用過其他家的試劑盒,感覺都不如華美可靠,以后會(huì)繼續(xù)使用,給我們科研很大的便利。合作愉快。
By 王老師
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