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Sheep Follicle Stimulating Hormone (FSH) ELISA kit

  • 中文名稱:
    綿羊卵泡刺激素(FSH)酶聯(lián)免疫試劑盒
  • 貨號(hào):
    CSB-E13170Sh
  • 規(guī)格:
    96T/48T
  • 價(jià)格:
    ¥3600/¥2500
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品描述:
    綿羊卵泡刺激素(FSH)酶聯(lián)免疫試劑盒(CSB-E13170Sh)為雙抗夾心法ELISA試劑盒,定量檢測(cè)樣本中的FSH含量。FSH即促卵泡生成素,是垂體前葉嗜堿性細(xì)胞分泌的糖蛋白激素。它在生殖系統(tǒng)中至關(guān)重要,參與調(diào)控卵泡發(fā)育和精子生成。研究機(jī)制主要圍繞其與受體結(jié)合,激活信號(hào)通路,調(diào)節(jié)生殖細(xì)胞的生長(zhǎng)、分化等過程,對(duì)治療生殖相關(guān)疾病意義重大。該產(chǎn)品為生殖生物學(xué)研究提供可靠工具,可用于探究繁殖周期調(diào)控機(jī)制、評(píng)估動(dòng)物繁殖力、監(jiān)測(cè)內(nèi)分泌功能異常等科研場(chǎng)景,同時(shí)支持畜牧業(yè)中優(yōu)良種畜的選育研究。適用于需要高重復(fù)性數(shù)據(jù)的體外實(shí)驗(yàn)研究。本品僅用于科研,不用于臨床診斷,產(chǎn)品具體參數(shù)及操作步驟詳見產(chǎn)品說明書。
  • 別名:
    FSHBFollitropin subunit beta ELISA kit; Follicle-stimulating hormone beta subunit ELISA kit; FSH-B ELISA kit; FSH-beta ELISA kit; Follitropin beta chain ELISA kit
  • 縮寫:
    FSH
  • Uniprot No.:
  • 種屬:
    Ovis aries (Sheep)
  • 反應(yīng)時(shí)間:
    1-5h
  • 樣本體積:
    50-100ul
  • 檢測(cè)波長(zhǎng):
    450 nm
  • 研究領(lǐng)域:
    Signal Transduction
  • 測(cè)定原理:
    quantitative
  • 測(cè)定方法:
    Sandwich
  • 精密度:
     
  • 線性度:
     
  • 回收率:
     
  • 標(biāo)準(zhǔn)曲線:
     
  • 數(shù)據(jù)處理:
  • 貨期:
    3-5 working days

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer. Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways. Follitropin is involved in follicle development and spermatogenesis in reproductive organs.
  • 基因功能參考文獻(xiàn):
    1. A novel GnRH response element between -750 bp and -232 bp of the ovine FSHB promoter. PMID: 23874399
    2. Data suggest that dietary components (phytoestrogens here) down-regulate basal secretion/total FSH (CGA+FSHB) production yet up-regulate gonadotropin-releasing hormone agonist-induced luteinizing hormone (CGA+LHB) secretion in gonadotrophs. PMID: 24050980
    3. In ewes, infusion with genistein decreased the level FSH-beta in the adenohypophysis. PMID: 15531133
    4. Activation of TAK1 (and probably p38-MAPK), but not Smad3, is necessary for triggering induction of oFSHbeta by activin. PMID: 16081641
    5. Activin gathers Smads and Smad-associated proteins at the promoter region to regulate expression of the ovine FSHB and overall follitropin production. PMID: 17584958

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  • 亞細(xì)胞定位:
    Secreted.
  • 蛋白家族:
    Glycoprotein hormones subunit beta family
  • 數(shù)據(jù)庫(kù)鏈接:

    KEGG: oas:443387

    UniGene: Oar.430