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ACADL Antibody

  • 中文名稱：
    ACADL兔多克隆抗體
  • 貨號(hào)：
    CSB-PA001125LA01HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • Western blot
      All lanes: ACADL antibody at 8µg/ml
      Lane 1: Mouse kidney tissue
      Lane 2: Mouse heart tissue
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 48 kDa
      Observed band size: 48 kDa
    • Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA001125LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA001125LA01HU at dilution of 1:100
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) ACADL Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    ACAD4 antibody; ACADL antibody; ACADL_HUMAN antibody; Acyl Coenzyme A dehydrogenase long chain antibody; Acyl-CoA dehydrogenase long chain antibody; FLJ94052 antibody; LCAD antibody; Long chain acyl CoA dehydrogenase antibody; Long-chain specific acyl-CoA dehydrogenase; mitochondrial antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human, Mouse
  • 免疫原：
    Recombinant Human Long-chain specific acyl-CoA dehydrogenase, mitochondrial protein (30-260AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated

    本頁面中的產(chǎn)品，ACADL Antibody (CSB-PA001125LA01HU)，的標(biāo)記方式是Non-conjugated。對(duì)于ACADL Antibody，我們還提供其他標(biāo)記。見下表：

    可提供標(biāo)記
    標(biāo)記方式 貨號(hào) 產(chǎn)品名稱 應(yīng)用
    HRP CSB-PA001125LB01HU ACADL Antibody, HRP conjugated ELISA
    FITC CSB-PA001125LC01HU ACADL Antibody, FITC conjugated
    Biotin CSB-PA001125LD01HU ACADL Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, WB, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:20-1:200
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Long-chain specific acyl-CoA dehydrogenase is one of the acyl-CoA dehydrogenases that catalyze the first step of mitochondrial fatty acid beta-oxidation, an aerobic process breaking down fatty acids into acetyl-CoA and allowing the production of energy from fats. The first step of fatty acid beta-oxidation consists in the removal of one hydrogen from C-2 and C-3 of the straight-chain fatty acyl-CoA thioester, resulting in the formation of trans-2-enoyl-CoA. Among the different mitochondrial acyl-CoA dehydrogenases, long-chain specific acyl-CoA dehydrogenase can act on saturated and unsaturated acyl-CoAs with 6 to 24 carbons with a preference for 8 to 18 carbons long primary chains.
  • 基因功能參考文獻(xiàn)：
    1. the fatty acid oxidation pathway and LCAD are factors contributing to the pathophysiology of pulmonary disease PMID: 24591516
    2. Sirtuin 3 (SIRT3) protein regulates long-chain acyl-CoA dehydrogenase by deacetylating conserved lysines near the active site. PMID: 24121500
    3. LCAD is minimally expressed in human skeletal muscle and likely does not play a significant role in long-chain fatty acid oxidation. PMID: 20363655
  • 相關(guān)疾病：
    Acyl-CoA dehydrogenase very long-chain deficiency (ACADVLD)
  • 亞細(xì)胞定位：
    Mitochondrion matrix.
  • 蛋白家族：
    Acyl-CoA dehydrogenase family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 88

    OMIM: 609576

    KEGG: hsa:33

    STRING: 9606.ENSP00000233710

    UniGene: Hs.471277