BEST3 Antibody

說(shuō)明書(shū)

產(chǎn)品詳情

Uniprot No.：

Q8N1M1
基因名：

BEST3
別名：

BEST3; VMD2L3; Bestrophin-3; Vitelliform macular dystrophy 2-like protein 3
宿主：

Rabbit
反應(yīng)種屬：

Human,Mouse
免疫原：

Human BEST3
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA,WB
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
儲(chǔ)存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Forms calcium-sensitive chloride channels. Permeable to bicarbonate.
基因功能參考文獻(xiàn)：
1. results demonstrated that Best-3 is an endogenous inhibitor of NF-kappaB signaling pathway in endothelial cells, suggesting that forced Best-3 expression may be a novel approach for the treatment of vascular inflammatory diseases. PMID: 25329324
2. These results suggest that an auto-inhibitory mechanism in C termini of bestrophin 3 may be universal among bestrophins investigated in the study. PMID: 17442670
亞細(xì)胞定位：

Cell membrane; Multi-pass membrane protein.
蛋白家族：

Bestrophin family
組織特異性：

Present in skeletal muscle and weakly in brain, spinal cord, bone marrow and retina.
數(shù)據(jù)庫(kù)鏈接：

HGNC: 17105

OMIM: 607337

KEGG: hsa:144453

STRING: 9606.ENSP00000332413

UniGene: Hs.280782