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CENPK Antibody

  • 中文名稱：
    CENPK兔多克隆抗體
  • 貨號(hào)：
    CSB-PA005214ESR1HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • Western blot
      All lanes: CENPK antibody at 3.98μg/ml
      Lane 1: PC-3 whole cell lysate
      Lane 2: 293T whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 32 kDa
      Observed band size: 32 kDa
    • Immunohistochemistry of paraffin-embedded human skin tissue using CSB-PA005214ESR1HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA005214ESR1HU at dilution of 1:100
    • Immunoprecipitating CENPK in Hela whole cell lysate
      Lane 1: Rabbit control IgG instead of CSB-PA005214ESR1HU in Hela whole cell lysate. For western blotting, a HRP-conjugated Protein G antibody was used as the secondary antibody (1/2000)
      Lane 2: CSB-PA005214ESR1HU (8μg) + Hela whole cell lysate (500μg)
      Lane 3: Hela whole cell lysate (10μg)
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) CENPK Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    CENPK
  • 別名：
    CENPK antibody; ICEN37 antibody; FKSG14 antibody; Centromere protein K antibody; CENP-K antibody; Interphase centromere complex protein 37 antibody; Protein AF-5alpha antibody; p33 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Centromere protein K protein (1-269AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, WB, IHC, IP
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
    IP 1:200-1:2000
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex. Acts in coordination with KNL1 to recruit the NDC80 complex to the outer kinetochore.
  • 相關(guān)疾病：
    Chromosomal aberrations involving CENPK are a cause of acute leukemias. Translocation t(5;11)(q12;q23) with KMT2A/MLL1.
  • 亞細(xì)胞定位：
    Nucleus. Chromosome, centromere. Chromosome, centromere, kinetochore. Note=Localizes exclusively in the centromeres. The CENPA-CAD complex is probably recruited on centromeres by the CENPA-NAC complex.
  • 蛋白家族：
    CENP-K/MCM22 family
  • 組織特異性：
    Detected in several fetal organs with highest levels in fetal liver. In adults, it is weakly expressed in lung and placenta.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 29479

    OMIM: 611502

    KEGG: hsa:64105

    STRING: 9606.ENSP00000242872

    UniGene: Hs.529778