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  4. EAPP Antibody

EAPP Antibody

  • 中文名稱：
    EAPP兔多克隆抗體
  • 貨號：
    CSB-PA007353LA01HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • Western Blot
      Positive WB detected in: 293 whole cell lysate
      All lanes: EAPP antibody at 3.2µg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 33 kDa
      Observed band size: 33 kDa
    • IHC image of CSB-PA007353LA01HU diluted at 1:400 and staining in paraffin-embedded human skeletal muscle tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) EAPP Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    EAPP
  • 別名：
    1810011O16Rik antibody; BM-036 antibody; BM036 antibody; C14orf11 antibody; E2F-associated phosphoprotein antibody; EAPP antibody; EAPP_HUMAN antibody; RGD1309624 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human E2F-associated phosphoprotein protein (1-285AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated

    本頁面中的產(chǎn)品，EAPP Antibody (CSB-PA007353LA01HU)，的標(biāo)記方式是Non-conjugated。對于EAPP Antibody，我們還提供其他標(biāo)記。見下表：

    可提供標(biāo)記
    標(biāo)記方式 貨號 產(chǎn)品名稱 應(yīng)用
    HRP CSB-PA007353LB01HU EAPP Antibody, HRP conjugated ELISA
    FITC CSB-PA007353LC01HU EAPP Antibody, FITC conjugated
    Biotin CSB-PA007353LD01HU EAPP Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, WB, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:5000
    IHC 1:200-1:500
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點(diǎn)詳情

  • 功能：
    May play an important role in the fine-tuning of both major E2F1 activities, the regulation of the cell-cycle and the induction of apoptosis. Promotes S-phase entry, and inhibits p14(ARP) expression.
  • 基因功能參考文獻(xiàn)：
    1. Independently of EAPP, E2F1 also increases the activity of the MDR1 promoter. PMID: 23542036
    2. results indicate that the level of EAPP is critical for cellular homeostasis PMID: 21258403
    3. EAPP modulates E2F-regulated transcription, stimulates proliferation, and may be involved in the malignant transformation of cells. PMID: 15716352
    4. Regulation of the EAPP promoter by GC-box binding proteins is reported. PMID: 18588995
  • 亞細(xì)胞定位：
    Cytoplasm. Nucleus.
  • 組織特異性：
    Ubiquitously expressed. Highest levels in heart, placenta, skeletal muscle and pancreas. Lower levels in brain, lung and kidney. In the brain, expressed in all regions with high levels in the cerebellum and cerebral cortex. Expressed in COS1 and transform
  • 數(shù)據(jù)庫鏈接：

    HGNC: 19312

    OMIM: 609486

    KEGG: hsa:55837

    STRING: 9606.ENSP00000250454

    UniGene: Hs.433269