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  4. GPA33 Antibody

GPA33 Antibody

  • 中文名稱：
    GPA33兔多克隆抗體
  • 貨號(hào)：
    CSB-PA857459EA01HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • Immunofluorescence staining of MCF-7 cells with CSB-PA857459EA01HU at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
    • Western Blot
      Positive WB detected in: K562 whole cell lysate, SH-SY5Y whole cell lysate
      All lanes: GPA33 antibody at 3.2µg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 36 kDa
      Observed band size: 50 kDa
    • Immunohistochemistry of paraffin-embedded human small intestine tissue using CSB-PA857459EA01HU at dilution of 1:100
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) GPA33 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    A33 antibody; Cell surface A33 antigen antibody; Cell surface A33 antigen precursor antibody; Glycoprotein A33 (transmembrane) antibody; Glycoprotein A33 antibody; Gpa33 antibody; GPA33_HUMAN antibody; MGC129986 antibody; MGC129987 antibody; OTTHUMP00000032346 antibody; Transmembrane glycoprotein A33 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Cell surface A33 antigen protein (22-235AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated

    本頁面中的產(chǎn)品，GPA33 Antibody (CSB-PA857459EA01HU)，的標(biāo)記方式是Non-conjugated。對(duì)于GPA33 Antibody，我們還提供其他標(biāo)記。見下表：

    可提供標(biāo)記
    標(biāo)記方式 貨號(hào) 產(chǎn)品名稱 應(yīng)用
    HRP CSB-PA857459EB01HU GPA33 Antibody, HRP conjugated ELISA
    FITC CSB-PA857459EC01HU GPA33 Antibody, FITC conjugated
    Biotin CSB-PA857459ED01HU GPA33 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, WB, IHC, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:5000
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    May play a role in cell-cell recognition and signaling.
  • 基因功能參考文獻(xiàn)：
    1. A33 shows similar sensitivity to but is more specific than CDX2 as an immunomarker of colorectal carcinoma PMID: 28226180
    2. A33 expression is directly correlated to colorectal tumor differentiation. PMID: 27272411
    3. Data indicate that EpCAM- and A33-Exos were released from the apical and basolateral surfaces, respectively. PMID: 23230278
    4. Data indicate positive staining was observed for both A33 expression and KRN330 binding from patients biopsied on Day 8, 9 or 14 following initial dosing of 3 mg/kg. PMID: 23294608
    5. The A33-dependent incorporation of B5 into extracellular enveloped vaccinia virions is mediated through an interaction between their lumenal domains. PMID: 22623777
    6. Increased interaction between vaccinia virus proteins A33 and B5 is detrimental to infectious extracellular enveloped virion production. PMID: 22623782
    7. cloning, chromosomal localizations, exon-intron structures and transcription start sites - target gene for the intestine-specific homeobox transcription factor, CDX1. PMID: 12114523
    8. Regulation of A33 antigen expression by GKLF. PMID: 12853980
    9. This work has demonstrated that the antigen is both highly immobile and extremely persistent-retaining its surface localization for a turnover halflife of greater than 2 days. PMID: 18236042

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  • 亞細(xì)胞定位：
    Membrane; Single-pass type I membrane protein.
  • 組織特異性：
    Expressed in normal gastrointestinal epithelium and in 95% of colon cancers.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 4445

    OMIM: 602171

    KEGG: hsa:10223

    STRING: 9606.ENSP00000356842

    UniGene: Hs.651244