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Your Good Partner in Biology Research

HCN3 Antibody

  • 中文名稱:
    HCN3兔多克隆抗體
  • 貨號:
    CSB-PA010218GA01HU
  • 規(guī)格:
    ¥3,900
  • 其他:

產(chǎn)品詳情

  • Uniprot No.:
  • 基因名:
    HCN3
  • 別名:
    HCN3; KIAA1535; Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human HCN3
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA,WB
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能:
    Hyperpolarization-activated potassium channel. May also facilitate the permeation of sodium ions.
  • 基因功能參考文獻(xiàn):
    1. Reduced HCN3 expression in aganglionic bowel suggests its potential role in Hirschsprung's disease pathophysiology. PMID: 25987789
    2. KCTD3 is an accessory subunit of native HCN3 complexes PMID: 23382386
    3. Genetic analysis in 48 Sudden unexpected death in epilepsy cases identified six novel and three previously reported nonsynonymous (amino acid changing) variants in HCN1 , HCN2, HCN3 and HCN4. PMID: 21615589
    4. human HCN3 is not modulated by intracellular cAMP, in contrast to other HCN subtypes PMID: 16043489
  • 亞細(xì)胞定位:
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族:
    Potassium channel HCN family
  • 組織特異性:
    Detected in brain.
  • 數(shù)據(jù)庫鏈接:

    HGNC: 19183

    OMIM: 609973

    KEGG: hsa:57657

    STRING: 9606.ENSP00000357342

    UniGene: Hs.706960