JSRP1 Antibody

說明書

產(chǎn)品詳情

Uniprot No.：

Q96MG2
基因名：

JSRP1
別名：

JSRP1 antibody; JP45 antibody; Junctional sarcoplasmic reticulum protein 1 antibody; Junctional-face membrane protein of 45 kDa homolog antibody; JP-45 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Human JSRP1
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity Purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產(chǎn)品提供形式：

Liquid
應用范圍：

ELISA,WB,IHC
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Involved in skeletal muscle excitation/contraction coupling (EC), probably acting as a regulator of the voltage-sensitive calcium channel CACNA1S. EC is a physiological process whereby an electrical signal (depolarization of the plasma membrane) is converted into a chemical signal, a calcium gradient, by the opening of ryanodine receptor calcium release channels. May regulate CACNA1S membrane targeting and activity.
基因功能參考文獻：
1. Data indicate that the presence of either one of these JP-45 variants decreased the sensitivity of the dihydropyridine receptor DHPR to activation. PMID: 22927026
2. The results may be explained by a modulatory effect of JP-45 related to its reported in vitro interaction with the dihydropyridine receptor and the SR Ca(2+) binding protein calsequestrin (CSQ). PMID: 16423849
亞細胞定位：

Sarcoplasmic reticulum membrane. Endoplasmic reticulum membrane.
數(shù)據(jù)庫鏈接：

HGNC: 24963

OMIM: 608743

KEGG: hsa:126306

STRING: 9606.ENSP00000300961

UniGene: Hs.330742