PGAP2 Antibody, HRP conjugated

說(shuō)明書(shū)

產(chǎn)品詳情

產(chǎn)品名稱(chēng)：

Rabbit anti-Homo sapiens (Human) PGAP2 Polyclonal antibody
Uniprot No.：

Q9UHJ9
基因名：

PGAP2
別名：

PGAP2; FRAG1; Post-GPI attachment to proteins factor 2; FGF receptor-activating protein 1
宿主：

Rabbit
反應(yīng)種屬：

Human
免疫原：

Recombinant Human Post-GPI attachment to proteins factor 2 protein (45-114AA)
免疫原種屬：

Homo sapiens (Human)
標(biāo)記方式：

HRP
克隆類(lèi)型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA
Protocols：

ELISA Protocol
儲(chǔ)存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Involved in the lipid remodeling steps of GPI-anchor maturation. Required for stable expression of GPI-anchored proteins at the cell surface.
基因功能參考文獻(xiàn)：
1. A Rare Variant in PGAP2 Causes Autosomal Recessive Hyperphosphatasia with Mental Retardation Syndrome, with a Mild Phenotype in Heterozygous Carriers. PMID: 29119105
2. Hypomorphic mutations in PGAP2, encoding a GPI-anchor-remodeling protein, cause autosomal-recessive intellectual disability. PMID: 23561846
3. PGAP2 mutations, affecting the GPI-anchor-synthesis pathway, cause hyperphosphatasia with mental retardation syndrome. PMID: 23561847
相關(guān)疾?。?/div>
Hyperphosphatasia with mental retardation syndrome 3 (HPMRS3)
亞細(xì)胞定位：

Golgi apparatus membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
蛋白家族：

PGAP2 family
組織特異性：

Ubiquitously expressed, with highest levels in testis and pancreas.
數(shù)據(jù)庫(kù)鏈接：

HGNC: 17893

OMIM: 614207

KEGG: hsa:27315

STRING: 9606.ENSP00000278243

UniGene: Hs.133968