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PGAP2 Antibody

  • 中文名稱：
    PGAP2兔多克隆抗體
  • 貨號：
    CSB-PA883397LA01HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA883397LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA883397LA01HU at dilution of 1:100
    • Immunofluorescent analysis of MCF-7 cells using CSB-PA883397LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) PGAP2 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    PGAP2
  • 別名：
    PGAP2; FRAG1; Post-GPI attachment to proteins factor 2; FGF receptor-activating protein 1
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Post-GPI attachment to proteins factor 2 protein (45-114AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated

    本頁面中的產(chǎn)品，PGAP2 Antibody (CSB-PA883397LA01HU)，的標(biāo)記方式是Non-conjugated。對于PGAP2 Antibody，我們還提供其他標(biāo)記。見下表：

    可提供標(biāo)記
    標(biāo)記方式 貨號 產(chǎn)品名稱 應(yīng)用
    HRP CSB-PA883397LB01HU PGAP2 Antibody, HRP conjugated ELISA
    FITC CSB-PA883397LC01HU PGAP2 Antibody, FITC conjugated
    Biotin CSB-PA883397LD01HU PGAP2 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, IHC, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Involved in the lipid remodeling steps of GPI-anchor maturation. Required for stable expression of GPI-anchored proteins at the cell surface.
  • 基因功能參考文獻：
    1. A Rare Variant in PGAP2 Causes Autosomal Recessive Hyperphosphatasia with Mental Retardation Syndrome, with a Mild Phenotype in Heterozygous Carriers. PMID: 29119105
    2. Hypomorphic mutations in PGAP2, encoding a GPI-anchor-remodeling protein, cause autosomal-recessive intellectual disability. PMID: 23561846
    3. PGAP2 mutations, affecting the GPI-anchor-synthesis pathway, cause hyperphosphatasia with mental retardation syndrome. PMID: 23561847
  • 相關(guān)疾病：
    Hyperphosphatasia with mental retardation syndrome 3 (HPMRS3)
  • 亞細胞定位：
    Golgi apparatus membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
  • 蛋白家族：
    PGAP2 family
  • 組織特異性：
    Ubiquitously expressed, with highest levels in testis and pancreas.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 17893

    OMIM: 614207

    KEGG: hsa:27315

    STRING: 9606.ENSP00000278243

    UniGene: Hs.133968