RADIL Antibody

說明書

產(chǎn)品詳情

Uniprot No.：

Q96JH8
基因名：

RADIL
別名：

RADIL antibody; KIAA1849 antibody; Ras-associating and dilute domain-containing protein antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Human RADIL
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產(chǎn)品提供形式：

Liquid
應用范圍：

ELISA,WB,IF
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunofluorescence (IF) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Downstream effector of Rap required for cell adhesion and migration of neural crest precursors during development.
基因功能參考文獻：
1. Studies indicate that Radil regulates neutrophil adhesion and motility by linking Rap1 to beta2-integrin activation. +++ ERROR +++ studies establish that Radil regulates neutrophil adhesion and motility by linking Rap1 to beta2-integrin activation. PMID: 23097489
2. It was shown that KIF14 associates with the PDZ domain of Radil and negatively regulates Rap1-mediated inside-out integrin activation by tethering Radil on microtubules. Radil is also important for breast cancer cell proliferation and metastasis. PMID: 23209302
3. Gbetagamma subunits enter in a protein complex with activated Rap1a and its effector Radil; this complex is required downstream of receptor stimulation for the activation of integrins and the positive modulation of cell-matrix adhesiveness. PMID: 20048162
蛋白家族：

RADIL family
數(shù)據(jù)庫鏈接：

HGNC: 22226

OMIM: 611491

KEGG: hsa:55698

STRING: 9606.ENSP00000382492

UniGene: Hs.667336