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SLC25A32 Antibody, FITC conjugated

  • 中文名稱：
    SLC25A32兔多克隆抗體, FITC偶聯(lián)
  • 貨號：
    CSB-PA872477LC01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) SLC25A32 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    SLC25A32
  • 別名：
    SLC25A32; MFT; MFTC; Mitochondrial folate transporter/carrier; Solute carrier family 25 member 32
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Mitochondrial folate transporter/carrier protein (44-88AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Transports folate across the inner membranes of mitochondria. Can also transport FAD across the mitochondrial inner membrane.
  • 基因功能參考文獻：
    1. These data demonstrate that the loss of functional Slc25a32 results in cranial neural tube defects (NTDs) in mice and has also been observed in a human NTD patient. PMID: 29666258
    2. A novel SLC25A32 homozygous variant is associated with severe neuromuscular phenotype. PMID: 28443623
    3. SLC25A32 gene polymorphism could be a risk factor for lower folate concentration and future fracture. PMID: 24354357
    4. identified residues in the walls and at the base of the transport cavity that are involved in substrate recognition by the MFT PMID: 21768094
    5. Patient with SLC25A32 deficiency was able to have a successful pregnancy after fertilization in vitro. PMID: 19362304

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  • 相關疾?。?/div>
    Exercise intolerance, riboflavin-responsive (RREI)
  • 亞細胞定位：
    Mitochondrion inner membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Mitochondrial carrier (TC 2.A.29) family
  • 組織特異性：
    Ubiquitous.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 29683

    OMIM: 610815

    KEGG: hsa:81034

    STRING: 9606.ENSP00000297578

    UniGene: Hs.532265