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fliC Antibody

Rare Species
  • 中文名稱：
    fliC兔多克隆抗體
  • 貨號：
    CSB-PA09734A0Rb
  • 規(guī)格：
    ￥440
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品描述：
    fliC polyclonal antibody CSB-PA09734A0Rb was produced in the rabbit immunized by using the Recombinant Escherichia coli Flagellin protein (2-498AA) as the immunogen. The target protein fliC is the subunit protein which polymerizes to form the filaments of bacterial flagella. Studies indicate that toll-like receptor 5 (TLR5) specifically interacts with flagellin, and is useful as an analytical recognition element for low concentrations of flagellin. Flagellin subunit FliC function as adhesins to piglet epithelial cells invasion.
    This Rabbit anti-Escherichia coli (strain K12) fliC Polyclonal antibody was tested in the ELISA. The non-conjugated IgG got purified by protein G and reached up to 95% in purity. It only reacts with the fliC proteins of Escherichia coli-origin and may be used to detect the endogenous levels of fliC protein.
  • 產(chǎn)品名稱：
    Rabbit anti-Escherichia coli fliC Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    fliC
  • 別名：
    fliC antibody; flaF antibody; hag antibody; b1923 antibody; JW1908Flagellin antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Escherichia coli
  • 免疫原：
    Recombinant Escherichia coli Flagellin protein (2-498AA)
  • 免疫原種屬：
    Escherichia coli
  • 標(biāo)記方式：
    Non-conjugated

    本頁面中的產(chǎn)品，fliC Antibody (CSB-PA09734A0Rb)，的標(biāo)記方式是Non-conjugated。對于fliC Antibody，我們還提供其他標(biāo)記。見下表：

    可提供標(biāo)記
    標(biāo)記方式 貨號 產(chǎn)品名稱 應(yīng)用
    HRP CSB-PA09734B0Rb fliC Antibody, HRP conjugated ELISA
    FITC CSB-PA09734C0Rb fliC Antibody, FITC conjugated
    Biotin CSB-PA09734D0Rb fliC Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
  • 基因功能參考文獻：
    1. Studies indicate that toll-like receptor 5 (TLR5) specifically interacts with flagellin, and is useful as an analytical recognition element for low concentrations of flagellin. PMID: 24881544
    2. Flagellin subunit FliC function as adhesins to piglet epithelial cells invasion. PMID: 23746569
    3. Results showed a reproducible and clear cut classification with molecular polymorphism of gene rfb cluster and flagella gene fliC. PMID: 19656466
    4. Flagellin in E. coli Nissle 1917 is the major stimulatory factor of human beta-defensin. PMID: 17283097
    5. Relations between the diversity of the fliC gene conditioning flagellum protein in E. coli and the source of the strain origin are presented PMID: 17702465
    6. Flagellin expression by uropathogenic Escherichia coli coincides with ascension of the ureters and colonization of the kidney. PMID: 17925449
    7. This study demonstrated that infection of intestinal epithelial cells by A/E pathogens can trigger an array of proinflammatory responses from epithelial cells through both FliC-dependent and -independent pathways. PMID: 18227166
    8. Insertion of Cys-derived thiol residues in the E. coli FliC protein increased Au(III) sorption and reduction onto the surface of the flagellar filament and resulted in the production of stabilized Au(0) nanoparticles of approximately 20-50 nm diameter. PMID: 18819156
    9. Binding of a fliC(H7) mutant O157 strain to rectal epithelium was significantly reduced as was binding of the flagellated wild-type strain following incubation with H7-specific antibodies. PMID: 19016776
    10. Increased IL-8 levels mainly depended on flagellin expression as fliC-negative EPEC did not elicit a significant IL-8 response despite increased mucosal colonization compared with wild-type EPEC. PMID: 19134113
    11. FliC is secreted by the LEE-encoded type III secretion system and stimulates TLR5 signalling but does not confer motility. PMID: 19200386

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  • 亞細(xì)胞定位：
    Secreted. Bacterial flagellum.
  • 蛋白家族：
    Bacterial flagellin family
  • 數(shù)據(jù)庫鏈接：

    KEGG: ecj:JW1908

    STRING: 316407.1736591