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CLDN6 Recombinant Monoclonal Antibody

  • 中文名稱：
    CLDN6重組抗體
  • 貨號(hào)：
    CSB-RA005508MA2HU
  • 規(guī)格：
    ￥1320
  • 圖片：
    • The Binding Activity of Human CLDN6 with Anti-CLDN6 recombinant antibody
      Activity: Measured by its binding ability in a functional ELISA. Immobilized Human CLDN6 (CSB-MP005508HU(A4)) at 10 μg/mL can bind Anti-CLDN6 recombinant antibody. The EC50 is 2.033-2.415 ng/mL. The VLPs (CSB-MP3838) is negative control.
    • Untransfected HEK-293T cells (green line) and transfected Human CLDN6 HEK-293T stable cells (red line) were stained with anti-CLDN6 antibody (2μg/1*106cells), washed and then followed by APC-conjugated anti-Human IgG Fc antibody and analyzed with flow cytometry.
    • Untransfected MC38 cells (green line) and transfected Human CLDN6 MC38 stable cells (red line) were stained with anti-CLDN6 antibody (2μg/1*106cells), washed and then followed by APC-conjugated anti-Human IgG Fc antibody and analyzed with flow cytometry.
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品描述：
    CLDN6 Recombinant Monoclonal Antibody（Code: CSB-RA005508MA2HU）是針對(duì)緊密連接蛋白家族成員CLDN6開發(fā)的高特異性抗體。CLDN6是一種跨膜蛋白，在維持細(xì)胞極性及細(xì)胞間屏障功能中發(fā)揮重要作用，其表達(dá)異常與多種組織發(fā)育異常及病理過程相關(guān)。本產(chǎn)品經(jīng)ELISA和流式細(xì)胞術(shù)（FC）嚴(yán)格驗(yàn)證，可特異性識(shí)別天然構(gòu)象的CLDN6蛋白，推薦使用稀釋度為FC 1:50-1:200。該抗體采用重組表達(dá)技術(shù)生產(chǎn)，具備優(yōu)異的批次穩(wěn)定性和低交叉反應(yīng)性，適用于體外實(shí)驗(yàn)中對(duì)CLDN6蛋白的定性及半定量檢測(cè)。在科研應(yīng)用中，該抗體可支持腫瘤生物學(xué)研究中CLDN6表達(dá)模式分析、上皮細(xì)胞屏障功能調(diào)控機(jī)制探索，以及藥物靶點(diǎn)篩選等相關(guān)實(shí)驗(yàn)，為研究細(xì)胞間連接蛋白在生理病理中的作用提供可靠工具。
  • 基因名：
  • 別名：
    Claudin-6 antibody; Claudin6 antibody; CLD6_HUMAN antibody; CLDN 6 antibody; CLDN6 antibody; OTTHUMP00000159248 antibody; Skullin 2 antibody; Skullin antibody; UNQ757/PRO1488 antibody
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human CLDN6 protein
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 克隆類型：
    Monoclonal
  • 抗體亞型：
    hIgG1
  • 純化方式：
    Affinity-chromatography
  • 克隆號(hào)：
    6D4
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, FC
  • 推薦稀釋比：
    Application Recommended Dilution
    FC 1:50-1:200
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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