Claudin-18.2 Recombinant Monoclonal Antibody
-
中文名稱:Claudin-18.2重組抗體
-
貨號(hào):CSB-RA005498A1HU
-
規(guī)格:¥1320
-
圖片:
-
Untransfected KATO3 cells surface (green line), transfected Human CLDN18.2 KATO3 stable cells surface (red line) and transfected Human CLDN18.1 NIH-3T3 stable cells surface (blue line) were stained with anti-CLDN18.2 antibody (2μg/1*106 cells), washed and then followed by FITC-conjugated anti-Human IgG Fc antibody and analyzed with flow cytometry.
-
The Binding Activity of Human CLDN18.2 with Anti-CLDN18.2 recombinant antibody.
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human CLDN18.2 (CSB-MP005498HU(A5)) at 5 μg/mL can bind Anti-CLDN18.2 recombinant antibody, the EC50 is 6.554-27.87 ng/mL.
-
-
其他:
產(chǎn)品詳情
-
產(chǎn)品描述:CSB-RA005498A1HU Claudin-18.2重組單克隆抗體是針對(duì)緊密連接蛋白家族成員Claudin-18.2研發(fā)的高特異性科研試劑。該靶點(diǎn)通過調(diào)控上皮細(xì)胞間緊密連接參與屏障功能維持,其亞型Claudin-18.2在胃癌、胰腺癌等消化道腫瘤中呈現(xiàn)特異性高表達(dá),成為腫瘤生物學(xué)研究的重要生物標(biāo)志物。本抗體經(jīng)ELISA和流式細(xì)胞術(shù)(FC)雙重驗(yàn)證,在FC應(yīng)用中推薦使用1:50-1:200的稀釋范圍,可精準(zhǔn)識(shí)別天然構(gòu)象的膜表面抗原,適用于活細(xì)胞或固定化樣本的定量檢測(cè)。該產(chǎn)品憑借優(yōu)異的批間一致性和低交叉反應(yīng)特性,可支持腫瘤細(xì)胞表面標(biāo)記物分析、靶向藥物體外篩選模型構(gòu)建以及腫瘤微環(huán)境中細(xì)胞亞群分選等研究場(chǎng)景,為探索Claudin-18.2在腫瘤發(fā)生、轉(zhuǎn)移及耐藥機(jī)制中的功能提供可靠工具,助力抗腫瘤藥物開發(fā)及轉(zhuǎn)化醫(yī)學(xué)研究。本產(chǎn)品嚴(yán)格限定于體外實(shí)驗(yàn)及基礎(chǔ)科研用途。
-
Uniprot No.:
-
基因名:
-
別名:Claudin-18, CLDN18
-
反應(yīng)種屬:Human
-
免疫原:Recombinant Human Claudin-18.2 protein
-
免疫原種屬:Homo sapiens (Human)
-
標(biāo)記方式:Non-conjugated
-
克隆類型:Monoclonal
-
抗體亞型:hIgG1
-
純化方式:Affinity-chromatography
-
克隆號(hào):9C2
-
濃度:It differs from different batches. Please contact us to confirm it.
-
保存緩沖液:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
產(chǎn)品提供形式:Liquid
-
應(yīng)用范圍:ELISA, FC
-
推薦稀釋比:
Application Recommended Dilution FC 1:50-1:200 -
Protocols:
-
儲(chǔ)存條件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
貨期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
-
用途:For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評(píng)價(jià)
實(shí)驗(yàn)應(yīng)用:IHC, FC, ELISA
樣品信息: 人胃黏膜細(xì)胞
稀釋比:1:100
產(chǎn)品評(píng)價(jià): 我使用CSB-RA005498A1HU的抗體,進(jìn)行ELISA和WB檢測(cè)人的細(xì)胞,WB檢測(cè)結(jié)果條帶較單一,檢測(cè)條帶大小與預(yù)期的一致,ELISA檢測(cè)EC50 為2.623-14.06 ng/mL。抗體特異性好,靈敏度高。
By 彭老師
實(shí)驗(yàn)應(yīng)用:FC
樣品信息:人來源細(xì)胞
稀釋比:1.100
產(chǎn)品評(píng)價(jià): 正常流式過程。
By 付老師
相關(guān)產(chǎn)品
Most popular with customers
-
YWHAB Recombinant Monoclonal Antibody
Applications: ELISA, WB, IHC, IF, FC
Species Reactivity: Human, Mouse, Rat
-
Phospho-YAP1 (S127) Recombinant Monoclonal Antibody
Applications: ELISA, WB, IHC
Species Reactivity: Human
-
-
-
-
-
-