APOE
APOE，即載脂蛋白E，別名 AD2、APOEA、LDLCQ5、LPG。APOE是一種多態(tài)性蛋白，由肝臟、小腸和大腦等組織產(chǎn)生，主要功能是結(jié)合脂質(zhì)并形成脂蛋白顆粒，介導(dǎo)脂質(zhì)在體內(nèi)的運輸和代謝。APOE的作用機制涉及與多種細胞表面受體的相互作用，如低密度脂蛋白受體（LDLR）、清道夫受體BI（SR-BI）等，通過這些受體介導(dǎo)脂蛋白的內(nèi)吞和脂質(zhì)的細胞內(nèi)運輸。APOE4是阿爾茨海默病最強的遺傳風(fēng)險因子之一，其與某些免疫細胞表面的受體LilrB3特異性結(jié)合，可能通過干擾小膠質(zhì)細胞的吞噬功能，促進β-淀粉樣蛋白（Aβ）沉積，從而增加阿爾茨海默病的發(fā)病風(fēng)險。APOE不僅在脂質(zhì)代謝中發(fā)揮關(guān)鍵作用，還與多種疾病的發(fā)生發(fā)展密切相關(guān)。APOE的這些多態(tài)性為研究脂質(zhì)代謝、神經(jīng)系統(tǒng)疾病以及開發(fā)新的治療策略提供了重要的分子基礎(chǔ)。
熱銷產(chǎn)品
APOE Antibody (CSB-PA07599A0Rb)
驗證數(shù)據(jù)
Immunofluorescence staining of HepG2 cells with CSB-PA07599A0Rb at 1:333, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
IHC image of CSB-PA07599A0Rb diluted at 1:1000 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
Human apolipoprotein E (Apo-E) ELISA Kit (CSB-E09748h)
驗證數(shù)據(jù)
貨號：CSB-E09748h
規(guī)格：96T/48T
靈敏度：3.9 ng/mL
檢測范圍：15.62 ng/mL-1000 ng/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
APOE Antibodies
APOE for Mus musculus (Mouse)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA001936LC01MO | Apoe Antibody, FITC conjugated | Mouse | |
| CSB-PA001936LA01MO | Apoe Antibody | Mouse | ELISA, WB |
| CSB-PA001936LD01MO | Apoe Antibody, Biotin conjugated | Mouse | ELISA |
| CSB-PA001936LB01MO | Apoe Antibody, HRP conjugated | Mouse | ELISA |
APOE for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA227407 | APOE Antibody | Human | ELISA,WB |
| CSB-PA009485 | APOE Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA009486 | APOE Antibody | Human | WB, ELISA |
| CSB-PA07599A0Rb | APOE Antibody | Human | ELISA, IHC, IF |
| CSB-PA07599B0Rb | APOE Antibody, HRP conjugated | Human | ELISA |
| CSB-PA07599C0Rb | APOE Antibody, FITC conjugated | Human | |
| CSB-PA07599D0Rb | APOE Antibody, Biotin conjugated | Human | ELISA |
APOE Proteins
APOE Proteins for Oryctolagus cuniculus (Rabbit)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP001936RB CSB-BP001936RB CSB-MP001936RB CSB-EP001936RB-B |
Recombinant Rabbit Apolipoprotein E (APOE) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP001936RB | Recombinant Rabbit Apolipoprotein E (APOE), partial | E.coli |
| CSB-EP001936RBb3 | Recombinant Rabbit Apolipoprotein E (APOE), partial | E.coli |
| CSB-EP001936RBb7 | Recombinant Rabbit Apolipoprotein E (APOE), partial | E.coli |
APOE Proteins for Sus scrofa (Pig)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP001936PI CSB-EP001936PI CSB-BP001936PI CSB-MP001936PI CSB-EP001936PI-B |
Recombinant Pig Apolipoprotein E (APOE) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
APOE Proteins for Canis familiaris (Dog) (Canis lupus familiaris)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP001936DO CSB-BP001936DO CSB-MP001936DO CSB-EP001936DO-B |
Recombinant Dog Apolipoprotein E (APOE) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
APOE Proteins for Cavia porcellus (Guinea pig)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP001936GU CSB-EP001936GU CSB-BP001936GU CSB-MP001936GU CSB-EP001936GU-B |
Recombinant Guinea pig Apolipoprotein E (APOE) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
APOE Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP001936HU CSB-EP001936HU CSB-BP001936HU CSB-MP001936HU CSB-EP001936HU-B |
Recombinant Human Apolipoprotein E (APOE) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
APOE Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP001936MO | Recombinant Mouse Apolipoprotein E (Apoe) | Yeast |
| CSB-EP001936MO | Recombinant Mouse Apolipoprotein E (Apoe) | E.coli |
| CSB-BP001936MO | Recombinant Mouse Apolipoprotein E (Apoe) | Baculovirus |
| CSB-MP001936MO | Recombinant Mouse Apolipoprotein E (Apoe) | Mammalian cell |
| CSB-EP001936MOc7 | Recombinant Mouse Apolipoprotein E (Apoe) | E.coli |
APOE Proteins for Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP001936MOV CSB-BP001936MOV CSB-MP001936MOV CSB-EP001936MOV-B |
Recombinant Macaca fascicularis Apolipoprotein E (APOE) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
APOE Proteins for Rattus norvegicus (Rat)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP001936RA CSB-BP001936RA CSB-MP001936RA CSB-EP001936RA-B |
Recombinant Rat Apolipoprotein E (Apoe) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
APOE Proteins for Papio anubis (Olive baboon)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP001936ERI CSB-EP001936ERI CSB-BP001936ERI CSB-MP001936ERI CSB-EP001936ERI-B |
Recombinant Papio anubis Apolipoprotein E (APOE) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
APOE Proteins for Ovis aries (Sheep)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP001936SH CSB-EP001936SH CSB-BP001936SH CSB-MP001936SH CSB-EP001936SH-B |
Recombinant Sheep Apolipoprotein E (APOE) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
APOE Proteins for Zalophus californianus (California sealion)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP001936ZAC CSB-EP001936ZAC CSB-BP001936ZAC CSB-MP001936ZAC CSB-EP001936ZAC-B |
Recombinant Zalophus californianus Apolipoprotein E (APOE) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
APOE Proteins for Gorilla gorilla gorilla (Lowland gorilla)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP001936GGZ CSB-EP001936GGZ CSB-BP001936GGZ CSB-MP001936GGZ CSB-EP001936GGZ-B |
Recombinant Gorilla gorilla gorilla Apolipoprotein E (APOE) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
APOE Proteins for Hylobates lar (Common gibbon)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP001936HXW CSB-EP001936HXW CSB-BP001936HXW CSB-MP001936HXW CSB-EP001936HXW-B |
Recombinant Hylobates lar Apolipoprotein E (APOE) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
APOE Proteins for Tupaia glis (Tree shrew)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP001936TJH CSB-EP001936TJH CSB-BP001936TJH CSB-MP001936TJH CSB-EP001936TJH-B |
Recombinant Tupaia glis Apolipoprotein E (APOE) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
APOE Proteins for Pan troglodytes (Chimpanzee)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP001936EQV CSB-EP001936EQV CSB-BP001936EQV CSB-MP001936EQV CSB-EP001936EQV-B |
Recombinant Pan troglodytes Apolipoprotein E (APOE) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
APOE Proteins for Pongo pygmaeus (Bornean orangutan)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP001936EXP CSB-EP001936EXP CSB-BP001936EXP CSB-MP001936EXP CSB-EP001936EXP-B |
Recombinant Pongo pygmaeus Apolipoprotein E (APOE) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
APOE Proteins for Macaca mulatta (Rhesus macaque)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP001936MOW CSB-BP001936MOW CSB-MP001936MOW CSB-EP001936MOW-B |
Recombinant Macaca mulatta Apolipoprotein E (APOE) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
APOE Proteins for Saimiri sciureus (Common squirrel monkey)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP001936SWD CSB-EP001936SWD CSB-BP001936SWD CSB-MP001936SWD CSB-EP001936SWD-B |
Recombinant Saimiri sciureus Apolipoprotein E (APOE)partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
APOE ELISA Kit
APOE ELISA Kit for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E09748h | Human apolipoprotein E (Apo-E) ELISA Kit | serum, plasma, cell culture supernates, tissue homogenates | 3.9 ng/mL |
APOE ELISA Kit for Monkey
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-EL001936RH | Monkey Apolipoprotein E(APOE) ELISA kit | serum, plasma, cell culture supernates, saliva, tissue homogenates | 1.56 ng/mL |
APOE ELISA Kit for Mus musculus (Mouse)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E09750m | Mouse apolipoprotein E (Apo-E) ELISA Kit | serum, plasma, cell culture supernates, tissue homogenates | 1.56 ng/mL |
APOE ELISA Kit for Rattus norvegicus (Rat)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E09749r | Rat apolipoprotein E (Apo-E) ELISA Kit | serum, plasma, tissue homogenates, cell culture supernates | 15.6 ng/mL |
APOE ELISA Kit for Sus scrofa (Pig)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E17889p | Pig apolipoprotein E (Apo-E) ELISA Kit | serum, plasma, tissue homogenates | 7.81 ng/mL |
