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CTSS

CTSS,即組織蛋白酶S,別名CathepsinS、Cats、CatS。CTSS由人類CTSS基因編碼,該基因位于1號(hào)染色體的1q21.3區(qū)域。CTSS是一種溶酶體半胱氨酸蛋白酶,屬于肽酶C1家族,參與將抗原蛋白降解為肽以呈遞到MHCII類分子上。CTSS還具有彈性蛋白酶活性,在細(xì)胞外可以重塑細(xì)胞外基質(zhì)的成分。CTSS與多種炎癥和自身免疫性疾病的病理學(xué)有關(guān),并且由于其彈性蛋白酶活性,在某些肺部疾病中起著重要作用。CTSS的異常表達(dá)和調(diào)節(jié)與包括肺部疾病在內(nèi)的多種疾病的發(fā)病機(jī)制有關(guān),例如肺纖維化,CTSS過(guò)表達(dá)導(dǎo)致多種病理過(guò)程,包括肺纖維化,CTSS分泌增加和細(xì)胞外基質(zhì)重塑加速。

熱銷產(chǎn)品

Recombinant Human Cathepsin S (CTSS) (CSB-EP006204HU)

驗(yàn)證數(shù)據(jù)

CSB-EP006204HU

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

CTSS Recombinant Monoclonal Antibody (CSB-RA788455A0HU)

驗(yàn)證數(shù)據(jù)

CSB-RA788455A0HU

IHC image of CSB-RA788455A0HU diluted at 1:100 and staining in paraffin-embedded human tonsil tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.

CSB-RA788455A0HU

IHC image of CSB-RA788455A0HU diluted at 1:100 and staining in paraffin-embedded human kidney tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.

Human Cathepsin S (CTSS) ELISA Kit (CSB-E13722h)

驗(yàn)證數(shù)據(jù)

CSB-E13722h 標(biāo)準(zhǔn)曲線

貨號(hào):CSB-E13722h

規(guī)格:96T/48T

靈敏度:15.6 pg/mL

檢測(cè)范圍:62.5 pg/mL- 4000 pg/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

CTSS Antibodies

CTSS for Homo sapiens (Human)

CTSS for Mus musculus (Mouse)

CTSS Proteins

CTSS Proteins for Rattus norvegicus (Rat)

CTSS Proteins for Homo sapiens (Human)

CTSS Proteins for Bos taurus (Bovine)

CTSS Proteins for Mus musculus (Mouse)

CTSS Proteins for Canis familiaris (Dog) (Canis lupus familiaris)

CTSS Proteins for Saimiri boliviensis boliviensis (Bolivian squirrel monkey)

CTSS ELISA Kit

CTSS ELISA Kit for Homo sapiens (Human)

CTSS ELISA Kit for Mus musculus (Mouse)

CTSS ELISA Kit for Rattus norvegicus (Rat)