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  4. Canine Fibroblast Growth Factor 23 (FGF23) ELISA Kit

Canine Fibroblast Growth Factor 23 (FGF23) ELISA Kit

  • 中文名稱：
    犬成纖維細(xì)胞生長因子23(FGF23)酶聯(lián)免疫試劑盒
  • 貨號：
    CSB-E17661c
  • 規(guī)格：
    96T/48T
  • 價(jià)格：
    ￥3800/￥2500
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品描述：
    犬成纖維細(xì)胞生長因子23(FGF23)酶聯(lián)免疫試劑盒（CSB-E17661c）為雙抗夾心法ELISA試劑盒，定量檢測血清、血漿、組織勻漿樣本中的FGF23含量。FGF23（成纖維細(xì)胞生長因子23）是一種由骨骼和腎臟分泌的激素，主要參與調(diào)節(jié)磷酸鹽和鈣的代謝。其研究背景涉及慢性腎病、低磷血癥等疾病。FGF23通過與Klotho蛋白結(jié)合，調(diào)節(jié)腎小管對磷酸鹽的重吸收，影響維生素D代謝和甲狀旁腺激素的分泌。研究機(jī)制主要圍繞其與骨骼、腎臟和神經(jīng)系統(tǒng)之間的相互作用，以及在不同疾病狀態(tài)下的功能變化。試劑盒檢測范圍為3.12 pg/mL-200 pg/mL，適用于科研領(lǐng)域中對犬類慢性腎病、鈣磷代謝紊亂及相關(guān)內(nèi)分泌疾病的機(jī)制探索，亦可用于動物模型中骨礦化異?；蚣に卣{(diào)控路徑的基礎(chǔ)研究本品僅用于科研，不用于臨床診斷，產(chǎn)品具體參數(shù)及操作步驟詳見產(chǎn)品說明書。
  • 別名：
    ADHR, HPDR2, HYPF, PHPTC, tumor-derived hypophosphatemia inducing factor
  • 縮寫：
  • 種屬：
    Canis lupus familiaris (Dog) (Canis familiaris)
  • 樣本類型：
    serum, plasma, tissue homogenates
  • 檢測范圍：
    3.12 pg/mL-200 pg/mL
  • 靈敏度：
    0.78 pg/mL
  • 反應(yīng)時間：
    1-5h
  • 樣本體積：
    50-100ul
  • 檢測波長：
    450 nm
  • 研究領(lǐng)域：
    Signal Transduction
  • 測定原理：
    quantitative
  • 測定方法：
    Sandwich
  • 精密度：
    Intra-assay Precision (Precision within an assay): CV%<8%
    Three samples of known concentration were tested twenty times on one plate to assess.
    Inter-assay Precision (Precision between assays): CV%<10%
    Three samples of known concentration were tested in twenty assays to assess.
  • 線性度：
    To assess the linearity of the assay, samples were spiked with high concentrations of canine FGF23 in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.
    SampleSerum(n=4)
    1:1Average %98
    Range %95-101
    1:2Average %87
    Range %83-91
    1:4Average %98
    Range %94-102
    1:8Average %84
    Range %81-86
  • 回收率：
    The recovery of canine FGF23 spiked to levels throughout the range of the assay in various matrices was evaluated. Samples were diluted prior to assay as directed in the Sample Preparation section.
    Sample TypeAverage % RecoveryRange
    Serum (n=5) 9085-95
    EDTA plasma (n=4)9390-96
  • 標(biāo)準(zhǔn)曲線：
    These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
    pg/mlOD1OD2AverageCorrected
    2002.865 2.758 2.812 2.635
    1002.462 2.401 2.432 2.255
    501.745 1.758 1.752 1.575
    251.065 1.120 1.093 0.916
    12.50.801 0.832 0.817 0.640
    6.250.517 0.521 0.519 0.342
    3.120.325 0.330 0.328 0.151
    00.178 0.176 0.177
  • 數(shù)據(jù)處理：
  • 貨期：
    3-5 working days

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