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中文名稱:人C肽(C-Peptide)酶聯(lián)免疫試劑盒
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貨號:CSB-E05066h
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規(guī)格:96T/48T
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價格:¥3600/¥2500
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其他:
產(chǎn)品詳情
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產(chǎn)品描述:人C肽(C-Peptide)酶聯(lián)免疫試劑盒(CSB-E05066h)為雙抗夾心法ELISA試劑盒,定量檢測血清、血漿、組織勻漿樣本中的C-Peptide含量。C-Peptide即C肽,是胰島素原在蛋白水解酶作用下分裂產(chǎn)生的等分子肽。它可反映胰島β細胞功能。研究機制上,通過檢測其水平輔助評估糖尿病患者胰島功能,為病情診斷、治療方案制定及預(yù)后判斷提供重要依據(jù)。試劑盒檢測范圍為0.5 ng/mL-8 ng/mL,靈敏度為0.25 ng/mL。適用于基礎(chǔ)醫(yī)學研究中動態(tài)監(jiān)測糖尿病模型動物的胰島功能變化,或體外實驗中對細胞分泌C肽水平的定量分析,為探索代謝調(diào)控機制、篩選潛在治療靶點提供可靠數(shù)據(jù)支持。在糖尿病發(fā)病機制研究、胰島功能評估及代謝性疾病相關(guān)藥物開發(fā)等領(lǐng)域具有科研價值。本品僅用于科研,不用于臨床診斷,產(chǎn)品具體參數(shù)及操作步驟詳見產(chǎn)品說明書。
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縮寫:C-Peptide
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種屬:Homo sapiens (Human)
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樣本類型:serum, plasma, tissue homogenates
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檢測范圍:0.5 ng/mL-8 ng/mL
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靈敏度:0.25 ng/mL
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反應(yīng)時間:1-5h
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樣本體積:50-100ul
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檢測波長:450 nm
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研究領(lǐng)域:Metabolism
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測定原理:quantitative
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測定方法:Sandwich
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精密度:
Intra-assay Precision (Precision within an assay): CV%<15%
Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision (Precision between assays): CV%<15%
Three samples of known concentration were tested in twenty assays to assess.
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標準曲線:
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
ng/ml
OD1
OD2
Average
Corrected
8
2.306
2.434
2.370
2.187
4
1.495
1.598
1.547
1.364
2
0.788
0.808
0.798
0.615
1
0.341
0.329
0.335
0.152
0.5
0.241
0.228
0.234
0.051
0
0.112
0.120
0.116
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數(shù)據(jù)處理:
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貨期:3-5 working days
引用文獻
- The Association of Fried Meat Consumption With the Gut Microbiota and Fecal Metabolites and Its Impact on Glucose Homoeostasis, Intestinal Endotoxin Levels, and Systemic Inflammation: A Randomized Controlled-Feeding Trial Jian Gao,Diabetes Care,2021
- NR4A1 Promotes Diabetic Nephropathy by Activating Mff-Mediated Mitochondrial Fission and Suppressing Parkin-Mediated Mitophagy Sheng J.et al,Cell Physiol Biochem,2018
相關(guān)產(chǎn)品
靶點詳情
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最新研究進展:C-肽是由胰島素的前體胰島素分子在轉(zhuǎn)化成胰島素過程中被剪切而產(chǎn)生的。雖然C-肽沒有胰島素的生物學活性,但它可以用來反映胰島素的分泌。近年來,有研究表明C-肽除了反映胰島素分泌外,還具有自身的生物學作用,如可以促進β細胞增殖和生存、促進脂肪細胞分化、減輕糖尿病腎病等作用。此外,C-肽還被用作糖尿病和胰島素抵抗的治療。例如,最近的一項研究表明,在2型糖尿病患者中,靜脈注射C-肽可以顯著降低血糖、胰島素劑量和甘油三酯水平,同時增加葡萄糖利用率。
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