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中文名稱:人血血小板衍生生長因子AB(PDGF-AB)酶聯(lián)免疫試劑盒
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貨號:CSB-E04701h
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規(guī)格:96T/48T
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價格:¥3200/¥2500
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其他:
產(chǎn)品詳情
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產(chǎn)品描述:人血血小板衍生生長因子AB(PDGF-AB)酶聯(lián)免疫試劑盒(CSB-E04701h)為雙抗夾心法ELISA試劑盒,定量檢測血清、血漿、組織勻漿樣本中的PDGF-AB含量。PDGF-AB是一種由血小板分泌的生長因子,由A和B鏈組成,參與調(diào)控纖維母細胞和平滑肌細胞等中胚層來源細胞的增殖和遷移。其研究機制涉及PDGF與PDGFRα和PDGFRβ受體的結合,激活下游信號通路,促進細胞增殖和血管生成。試劑盒檢測范圍為31.25 pg/mL-2000 pg/mL,靈敏度為7.8 pg/mL。適用于體外實驗中對PDGF-AB的定量分析,例如探究心血管疾病模型中的信號通路機制、評估藥物干預對細胞因子表達的影響,或通過組織樣本分析疾病相關分子標志物變化,為細胞生物學、病理學及藥理學研究提供可靠數(shù)據(jù)支持。本品僅用于科研,不用于臨床診斷,產(chǎn)品具體參數(shù)及操作步驟詳見產(chǎn)品說明書。
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縮寫:PDGF-AB
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種屬:Homo sapiens (Human)
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樣本類型:serum, plasma, tissue homogenates
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檢測范圍:31.25 pg/mL-2000 pg/mL
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靈敏度:7.8 pg/mL
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反應時間:1-5h
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樣本體積:50-100ul
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檢測波長:450 nm
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研究領域:Cancer
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測定原理:quantitative
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測定方法:Sandwich
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精密度:
Intra-assay Precision (Precision within an assay): CV%<8%
Three samples of known concentration were tested twenty times on one plate to assess.Inter-assay Precision (Precision between assays): CV%<10%Three samples of known concentration were tested in twenty assays to assess. -
線性度:
To assess the linearity of the assay, samples were spiked with high concentrations of human PDGF-AB in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.
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回收率:
The recovery of human PDGF-AB spiked to levels throughout the range of the assay in various matrices was evaluated. Samples were diluted prior to assay as directed in the Sample Preparation section.
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標準曲線:
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
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數(shù)據(jù)處理:
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貨期:3-5 working days
引用文獻
- Differences in injectable platelet-rich fibrin fraction of peripheral blood on the release of TGF-β1 and PDGF-AB S Suryono,Majalah Kedokteran Gigi Indonesia,2023
- A comparative study of the effects of concentrated growth factors in two different forms on osteogenesis in vitro Wang L,Molecular Medicine Reports,2019
- Chitosan scaffold enhances growth factor release in wound healing in von Willebrand disease Periayah MH. et al,Int J Clin Exp Med,2015
相關產(chǎn)品
靶點詳情
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最新研究進展:PDGF-AB是血小板源性生長因子(platelet-derived growth factor,PDGF)家族的一個亞型,由PDGF-A和PDGF-B兩個亞基組成。最近的研究表明,PDGF-AB參與了多種生物學過程,如細胞增殖、分化、遷移和細胞外基質(zhì)合成等。此外,PDGF-AB在多種疾病中也發(fā)揮著重要作用,如腫瘤、動脈粥樣硬化和組織損傷等。因此,PDGF-AB成為了治療靶點的研究熱點。一些研究已經(jīng)探索了PDGF-AB的抑制劑和抗體,以期望發(fā)現(xiàn)更有效的治療方案。
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