Monkey amyloid beta peptide 1-42,Aβ1-42 ELISA Kit
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中文名稱:猴β淀粉樣蛋白1-42(Aβ1-42)酶聯(lián)免疫試劑盒
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貨號(hào):CSB-E14398Mk
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規(guī)格:96T/48T
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價(jià)格:¥4200/¥3000
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其他:
產(chǎn)品詳情
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產(chǎn)品描述:猴β淀粉樣蛋白1-42(Aβ1-42)酶聯(lián)免疫試劑盒(CSB-E14398Mk)為雙抗夾心法ELISA試劑盒,定量檢測(cè)血清、血漿樣本中的Aβ1-42含量。Aβ1-42是一種由淀粉樣前體蛋白(APP)切割產(chǎn)生的β-淀粉樣蛋白,其在阿爾茨海默?。ˋD)的病理過(guò)程中扮演關(guān)鍵角色。研究表明,Aβ1-42的異常積累與AD的認(rèn)知障礙密切相關(guān),成為潛在的藥物靶點(diǎn)。通過(guò)降解Aβ1-42,可以減緩認(rèn)知功能的衰退,為AD的治療提供新思路。試劑盒檢測(cè)范圍為0.156 ng/mL-10 ng/mL,適用于神經(jīng)退行性疾病機(jī)制研究及藥物開(kāi)發(fā)評(píng)估;可廣泛應(yīng)用于阿爾茨海默病模型構(gòu)建、Aβ代謝通路研究、神經(jīng)保護(hù)藥物篩選等科研場(chǎng)景,特別適用于動(dòng)態(tài)監(jiān)測(cè)靈長(zhǎng)類動(dòng)物外周血中Aβ1 - 42濃度變化,為病理機(jī)制解析和干預(yù)策略開(kāi)發(fā)提供可靠工具本品僅用于科研,不用于臨床診斷,產(chǎn)品具體參數(shù)及操作步驟詳見(jiàn)產(chǎn)品說(shuō)明書。
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別名:Amyloid beta 42(ABeta 42),amyloid beta peptide 1-42,Aβ1-42,amyloid βpeptide 1-42
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縮寫:Aβ1-42
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種屬:Monkey
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樣本類型:serum, plasma
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檢測(cè)范圍:0.156 ng/mL-10 ng/mL
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靈敏度:0.039 ng/mL
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反應(yīng)時(shí)間:1-5h
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樣本體積:50-100ul
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檢測(cè)波長(zhǎng):450 nm
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研究領(lǐng)域:Neuroscience
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測(cè)定原理:quantitative
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測(cè)定方法:Sandwich
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精密度:
Intra-assay Precision (Precision within an assay): CV%<8% Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision (Precision between assays): CV%<10% Three samples of known concentration were tested in twenty assays to assess. -
標(biāo)準(zhǔn)曲線:
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed. ng/ml OD1 OD2 Average Corrected 10 2.692 2.789 2.741 2.601 5 2.014 1.997 2.006 1.866 2.5 1.242 1.301 1.272 1.132 1.25 0.679 0.665 0.672 0.532 0.625 0.503 0.500 0.502 0.362 0.312 0.299 0.305 0.302 0.162 0.156 0.245 0.260 0.253 0.113 0 0.141 0.138 0.140 -
數(shù)據(jù)處理:
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貨期:3-5 working days
引用文獻(xiàn)
- Correlations between serum levels of beta amyloid, cerebrospinal levels of tau and phospho tau, and delayed response tasks in young and aged cynomolgus Darusman HS et al,J Med Primatol.,2013
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