IL1A

IL1A，即白細胞介素1α，別名IL-1α、Hematopoietin-1、Lymphocyte-Activating Factor (LAF)、Endogenous Pyrogen (EP)、IL1F1等。它是一種由IL1A基因編碼的多效性細胞因子，主要由活化的巨噬細胞、中性粒細胞、上皮細胞和內(nèi)皮細胞產(chǎn)生。IL1A的作用機制涉及其前體蛋白在細胞內(nèi)的轉(zhuǎn)錄因子功能以及成熟形式在細胞外的信號傳導(dǎo)作用。IL1A前體在細胞核內(nèi)促進基因表達，調(diào)控細胞生長和分化。成熟形式的IL1A通過與細胞表面的IL-1受體IL1R1結(jié)合，觸發(fā)信號傳導(dǎo)復(fù)合物的形成，激活NF-kappa-B和MAPK通路，從而引發(fā)炎癥反應(yīng)和免疫應(yīng)答。在生物學意義上，IL1A在機體的炎癥反應(yīng)、免疫調(diào)節(jié)以及與多種疾病的關(guān)聯(lián)中發(fā)揮關(guān)鍵作用。它參與機體抗微生物感染、無菌炎癥、腫瘤相關(guān)疾病以及自發(fā)炎癥的調(diào)節(jié)。IL1A的異常表達與多種疾病有關(guān)，包括Fabry病、Schnitzler綜合征、多種自身免疫性疾病、血液腫瘤和肺部疾病等。因此，IL1A是炎癥和免疫相關(guān)疾病研究中的一個重要分子靶點，并且是臨床治療多種疾病的潛在標志物和治療靶點。

熱銷產(chǎn)品

Recombinant Human Interleukin-1 alpha (IL1A) (CSB-YP011613HU)

驗證數(shù)據(jù)

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

IL1A Antibody (CSB-PA584603)

驗證數(shù)據(jù)

The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA584603(IL1A Antibody) at dilution 1/60, on the right is treated with fusion protein. (Original magnification: ×200)

The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA584603(IL1A Antibody) at dilution 1/60, on the right is treated with fusion protein. (Original magnification: ×200)

Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Jurkat cells, Primary antibody: CSB-PA584603(IL1A Antibody) at dilution 1/666, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds

Human Interleukin 1α,IL-1α ELISA Kit (CSB-E04620h)

驗證數(shù)據(jù)

貨號：CSB-E04620h

規(guī)格：96T/48T

靈敏度：0.975 pg/ml.

檢測范圍：3.9 pg/ml-250 pg/ml.

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

IL1A Antibody

IL1A Protein

IL1A ELISA Kit

IL1A Antibodies

IL1A for Homo sapiens (Human)

產(chǎn)品貨號	產(chǎn)品名稱	種屬反應(yīng)性	應(yīng)用類型
CSB-PA06565A0Rb	IL1A Antibody	Human	ELISA
CSB-PA06565C0Rb	IL1A Antibody, FITC conjugated	Human
CSB-PA011613GA01HU	IL1A Antibody	Human	ELISA,WB
CSB-PA009537	IL1A Antibody	Human,Mouse,Rat	IHC, ELISA
CSB-PA107052	IL1A Antibody	Human	ELISA,IHC
CSB-PA584603	IL1A Antibody	Human	ELISA,WB,IHC

IL1A for Macaca mulatta

產(chǎn)品貨號	產(chǎn)品名稱	種屬反應(yīng)性	應(yīng)用類型
CSB-PA011613LA01MOW	IL1A Antibody	Macaca mulatta, Human	ELISA, WB

IL1A Proteins

IL1A Proteins for Capra hircus (Goat)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP011613GO CSB-EP011613GO CSB-BP011613GO CSB-MP011613GO CSB-EP011613GO-B	Recombinant Goat Interleukin-1 alpha (IL1A)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL1A Proteins for Sus scrofa (Pig)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP011613PI CSB-EP011613PI CSB-BP011613PI CSB-MP011613PI CSB-EP011613PI-B	Recombinant Pig Interleukin-1 alpha (IL1A)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL1A Proteins for Macaca mulatta (Rhesus macaque)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP011613MOW	Recombinant Macaca mulatta Interleukin-1 alpha (IL1A)	Yeast
CSB-AP003071MOW	Recombinant Macaca mulatta Interleukin-1 alpha (IL1A) (Active)	E.Coli
CSB-EP011613MOW	Recombinant Macaca mulatta Interleukin-1 alpha (IL1A)	E.coli
CSB-BP011613MOW CSB-MP011613MOW CSB-EP011613MOW-B	Recombinant Macaca mulatta Interleukin-1 alpha (IL1A)	Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL1A Proteins for Mus musculus (Mouse)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP011613MO CSB-EP011613MO CSB-BP011613MO CSB-MP011613MO CSB-EP011613MO-B	Recombinant Mouse Interleukin-1 alpha (Il1a)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-AP003251MO	Recombinant Mouse Interleukin-1 alpha protein (Il1a)	E.Coli
CSB-AP004721MO	Recombinant Mouse Interleukin-1 alpha (Il1a) (Active)	E.coli

IL1A Proteins for Homo sapiens (Human)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP011613HU	Recombinant Human Interleukin-1 alpha (IL1A)	Yeast
CSB-EP011613HUe0	Recombinant Human Interleukin-1 alpha (IL1A)	E.coli
CSB-EP011613HU	Recombinant Human Interleukin-1 alpha (IL1A)	E.coli
CSB-AP001661HU	Recombinant Human Interleukin-1 alpha protein (IL1A)	E.Coli
CSB-BP011613HU CSB-MP011613HU	Recombinant Human Interleukin-1 alpha (IL1A)	Baculovirus Mammalian cell
CSB-YP011613HUc7	Recombinant Human Interleukin-1 alpha (IL1A)	Yeast
CSB-AP004261HU	Recombinant Human Interleukin-1 alpha (IL1A) (Active)	E.coli
CSB-AP005801HU	Recombinant Human Interleukin-1 alpha (IL1A) (Active) (GMP)	E.Coli
CSB-EP011613HU-B	Recombinant Human Interleukin-1 alpha (IL1A),Biotinylated	E.coli

IL1A Proteins for Bos taurus (Bovine)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP011613BO CSB-EP011613BO CSB-BP011613BO CSB-MP011613BO CSB-EP011613BO-B	Recombinant Bovine Interleukin-1 alpha (IL1A)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL1A Proteins for Oryctolagus cuniculus (Rabbit)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP011613RB CSB-EP011613RB CSB-BP011613RB CSB-MP011613RB CSB-EP011613RB-B	Recombinant Rabbit Interleukin-1 alpha (IL1A)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL1A Proteins for Felis catus (Cat) (Felis silvestris catus)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP011613CA CSB-EP011613CA CSB-BP011613CA CSB-MP011613CA CSB-EP011613CA-B	Recombinant Cat Interleukin-1 alpha (IL1A)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL1A Proteins for Canis familiaris (Dog) (Canis lupus familiaris)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP011613DO CSB-EP011613DO CSB-BP011613DO CSB-MP011613DO CSB-EP011613DO-B	Recombinant Dog Interleukin-1 alpha (IL1A)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL1A Proteins for Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-BP011613MOV CSB-MP011613MOV CSB-EP011613MOV-B	Recombinant Macaca fascicularis Interleukin-1 alpha (IL1A)	Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL1A Proteins for Rattus norvegicus (Rat)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP011613RA CSB-EP011613RA CSB-BP011613RA CSB-MP011613RA CSB-EP011613RA-B	Recombinant Rat Interleukin-1 alpha (Il1a)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL1A Proteins for Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP011613DRI CSB-EP011613DRI CSB-BP011613DRI CSB-MP011613DRI CSB-EP011613DRI-B	Recombinant Cercocebus atys Interleukin-1 alpha (IL1A)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL1A Proteins for Ovis aries (Sheep)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP630687SH CSB-EP630687SH CSB-BP630687SH CSB-MP630687SH CSB-EP630687SH-B	Recombinant Sheep Interleukin-1 alpha (IL1A)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL1A Proteins for Equus caballus (Horse)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP636720HO CSB-EP636720HO CSB-BP636720HO CSB-MP636720HO CSB-EP636720HO-B	Recombinant Horse Interleukin-1 alpha (IL1A)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL1A Proteins for Bubalus carabanensis (Swamp type water buffalo) (Bubalus bubalis carabanensis)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP661675BAAW CSB-EP661675BAAW CSB-BP661675BAAW CSB-MP661675BAAW CSB-EP661675BAAW-B	Recombinant Bubalus carabanensis Interleukin-1 alpha (IL1A)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL1A Proteins for Cavia porcellus (Guinea pig)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP733672GU CSB-EP733672GU CSB-BP733672GU CSB-MP733672GU CSB-EP733672GU-B	Recombinant Guinea pig Interleukin-1 alpha (IL1A)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL1A Proteins for Lama glama (Llama)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP774725LBS CSB-EP774725LBS CSB-BP774725LBS CSB-MP774725LBS CSB-EP774725LBS-B	Recombinant Lama glama Interleukin-1 alpha (IL1A)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli