IL5

IL5，即白介素5，它主要由活化的T細胞產生，也可由某些人T細胞白血病細胞系、EB病毒轉化的B細胞以及嗜酸性粒細胞產生。IL5的作用機制涉及到與特定的細胞表面受體結合，其受體由IL-5Rα鏈和信號傳導亞基βc組成，形成高親和受體。IL5通過與IL-5Rα的低親和結合，再緊密結合βc二聚體，激活下游的信號傳導途徑，如JAK/STAT通路，進而促進嗜酸性粒細胞的分化、成熟、活化、遷移和存活。IL5在生物學上的意義主要體現(xiàn)在其對嗜酸性粒細胞相關生物學過程的調控作用。它在寄生蟲感染和過敏性疾病的發(fā)病機制中起到關鍵作用，特別是在嗜酸性粒細胞增多癥和某些變態(tài)反應性疾病中，IL5的水平會增高。IL5通過促進嗜酸性粒細胞的增殖和活化，增強其殺傷腫瘤細胞和病原體的能力，同時在粘膜免疫中也發(fā)揮重要作用。此外，IL5還參與調節(jié)B細胞的分化和抗體的產生，尤其是在IgA的合成中具有協(xié)同作用。因此，IL5是免疫應答中的一個重要細胞因子，對維持免疫平衡和防御機制具有重要影響。

熱銷產品

Recombinant Human Interleukin-5 (IL5) (CSB-MP011662HU)

驗證數據

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

The purity of IL5 was greater than 95% as determined by SEC-HPLC

IL5 Antibody (CSB-PA003033)

驗證數據

Western Blot analysis of HuvEc cells using IL-5 Polyclonal Antibody

Immunohistochemistry of paraffin-embedded human breast carcinoma tissue using CSB-PA003033 at dilution of 1:100

Rat Interleukin 5,IL-5 ELISA KIT (CSB-E07435r)

驗證數據

貨號：CSB-E07435r

規(guī)格：96T/48T

靈敏度：3.9 pg/mL

檢測范圍：15.6 pg/mL-1000 pg/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

IL5 Antibody

IL5 Protein

IL5 ELISA Kit

IL5 Antibodies

IL5 for Homo sapiens (Human)

產品貨號	產品名稱	種屬反應性	應用類型
CSB-PA003033	IL5 Antibody	Human,Mouse,Rat	WB, IHC, ELISA

IL5 Proteins

IL5 Proteins for Macaca mulatta (Rhesus macaque)

產品貨號	產品名稱	來源
CSB-YP011662MOW CSB-EP011662MOW CSB-BP011662MOW CSB-MP011662MOW CSB-EP011662MOW-B	Recombinant Macaca mulatta (Rhesus macaque) Interleukin-5 (IL5)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-AP003091MOW	Recombinant Rhesus Macaque Interleukin-5 protein (IL5) (Active)	E.Coli

IL5 Proteins for Bos taurus (Bovine)

產品貨號	產品名稱	來源
CSB-YP011662BO CSB-EP011662BO CSB-BP011662BO CSB-MP011662BO CSB-EP011662BO-B	Recombinant Bovine Interleukin-5 (IL5)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL5 Proteins for Mus musculus (Mouse)

產品貨號	產品名稱	來源
CSB-YP011662MO CSB-EP011662MO CSB-BP011662MO CSB-MP011662MO CSB-EP011662MO-B	Recombinant Mouse Interleukin-5 (Il5)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-AP003311MO	Recombinant Mouse Interleukin-5 protein (Il5)	E.Coli

IL5 Proteins for Equus caballus (Horse)

產品貨號	產品名稱	來源
CSB-YP011662HO CSB-EP011662HO CSB-BP011662HO CSB-MP011662HO CSB-EP011662HO-B	Recombinant Horse Interleukin-5 (IL5)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL5 Proteins for Cavia porcellus (Guinea pig)

產品貨號	產品名稱	來源
CSB-YP011662GU CSB-EP011662GU CSB-BP011662GU CSB-MP011662GU CSB-EP011662GU-B	Recombinant Guinea pig Interleukin-5 (IL5)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL5 Proteins for Felis catus (Cat) (Felis silvestris catus)

產品貨號	產品名稱	來源
CSB-YP011662CA CSB-EP011662CA CSB-BP011662CA CSB-MP011662CA CSB-EP011662CA-B	Recombinant Cat Interleukin-5 (IL5)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL5 Proteins for Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys)

產品貨號	產品名稱	來源
CSB-YP011662DRI CSB-EP011662DRI CSB-BP011662DRI CSB-MP011662DRI CSB-EP011662DRI-B	Recombinant Cercocebus atys Interleukin-5 (IL5)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL5 Proteins for Ovis aries (Sheep)

產品貨號	產品名稱	來源
CSB-YP637909SH CSB-EP637909SH CSB-BP637909SH CSB-MP637909SH CSB-EP637909SH-B	Recombinant Sheep Interleukin-5 (IL5)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL5 Proteins for Meriones unguiculatus (Mongolian jird) (Mongolian gerbil)

產品貨號	產品名稱	來源
CSB-YP733829MRA CSB-EP733829MRA CSB-BP733829MRA CSB-MP733829MRA CSB-EP733829MRA-B	Recombinant Meriones unguiculatus Interleukin-5 (IL5)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL5 Proteins for Canis familiaris (Dog) (Canis lupus familiaris)

產品貨號	產品名稱	來源
CSB-YP842539DO CSB-EP842539DO CSB-BP842539DO CSB-MP842539DO CSB-EP842539DO-B	Recombinant Dog Interleukin-5 (IL5)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL5 Proteins for Sigmodon hispidus (Hispid cotton rat)

產品貨號	產品名稱	來源
CSB-YP861706SZK CSB-EP861706SZK CSB-BP861706SZK CSB-MP861706SZK CSB-EP861706SZK-B	Recombinant Sigmodon hispidus Interleukin-5 (IL5)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL5 Proteins for Sus scrofa (Pig)

產品貨號	產品名稱	來源
CSB-YP863067PI	Recombinant Pig Interleukin-5 (IL5)	Yeast
CSB-EP863067PI	Recombinant Pig Interleukin-5 (IL5)	E.coli
CSB-BP863067PI CSB-MP863067PI CSB-EP863067PI-B	Recombinant Pig Interleukin-5 (IL5)	Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL5 Proteins for Macropus eugenii (Tammar wallaby)

產品貨號	產品名稱	來源
CSB-YP895944MPE CSB-EP895944MPE CSB-BP895944MPE CSB-MP895944MPE CSB-EP895944MPE-B	Recombinant Macropus eugenii Interleukin-5 (IL5)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL5 Proteins for Homo sapiens (Human)

產品貨號	產品名稱	來源
CSB-AP001721HU	Recombinant Human Interleukin-5 protein (IL5)	E.Coli
CSB-EP011662HU CSB-BP011662HU CSB-EP011662HU-B	Recombinant Human Interleukin-5 (IL5)	E.coli Baculovirus In Vivo Biotinylation in E.coli
CSB-YP011662HU	Recombinant Human Interleukin-5 (IL5)	Yeast
CSB-AP004291HU	Recombinant Human Interleukin-5 (IL5) (Active)	Mammalian cell
CSB-MP011662HU	Recombinant Human Interleukin-5 (IL5)	Mammalian cell
CSB-MP011662HUa0	Recombinant Human Interleukin-5 (IL5)	Mammalian cell
CSB-YP011662HUa0	Recombinant Human Interleukin-5 (IL5)	Yeast