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每年的10月29日是世界銀屑病日，由國(guó)際銀屑病協(xié)會(huì)（International Federation of Psoriasis Association，簡(jiǎn)稱IFPA）設(shè)立，旨在提高公眾對(duì)銀屑病的認(rèn)識(shí)和理解，支持銀屑病患者，并推動(dòng)對(duì)該疾病的研究和治療。2024年的世界銀屑病日主題是“家庭”（Family），強(qiáng)調(diào)銀屑病患者及其家庭成員在面對(duì)疾病挑戰(zhàn)時(shí)需要得到堅(jiān)定不移的支持。

銀屑病俗稱“牛皮癬”，是一種由環(huán)境因素刺激、多基因遺傳控制、免疫介導(dǎo)的皮膚病，可分為尋常型、關(guān)節(jié)病型、膿皰型和紅皮病型4種類型。其典型表現(xiàn)為鱗屑性紅斑或斑塊，局限于一處或全身廣泛分布。除了皮膚損害外，銀屑病還可能影響指甲、關(guān)節(jié)等部位，甚至伴隨多種系統(tǒng)合并癥，如代謝綜合征、炎癥性腸病、心血管疾病、精神障礙等。

近年來(lái)，銀屑病的藥物研發(fā)取得了顯著進(jìn)展，尤其是在生物制劑和小分子靶向藥物方面。在生物制劑方面，目前已有多種針對(duì)銀屑病的靶向抗體藥物上市或處于研發(fā)階段。包括TNF-α抑制劑、IL-12/23抑制劑、IL-23抑制劑、IL-17A抑制劑和IL-36受體抑制劑等。這些生物制劑通過(guò)靶向特定的炎癥介質(zhì)，可以有效控制銀屑病的癥狀。在小分子藥物方面，酪氨酸激酶2（TYK2）變構(gòu)抑制劑已獲批上市，適用于中重度斑塊狀銀屑病患者。此外，JAK抑制劑、PDE4抑制劑、NRF2刺激劑等也在研發(fā)中，這些藥物通過(guò)不同的信號(hào)通路干預(yù)銀屑病的發(fā)病機(jī)制。

華美生物提供銀屑病藥物開(kāi)發(fā)靶點(diǎn)蛋白、重組抗體、ELISA試劑盒等產(chǎn)品，助力基礎(chǔ)科研及藥物開(kāi)發(fā)。

銀屑病在研藥物靶點(diǎn)

銀屑病藥物靶點(diǎn)相關(guān)產(chǎn)品推薦

● 靶點(diǎn)蛋白

Recombinant Human Interleukin-17A (IL17A)
CSB-BP624104HU(M)

Recombinant Human Interleukin-2 (IL2)
CSB-MP011629HU

Recombinant Human Interleukin-6 (IL6)
CSB-YP011664HU

Recombinant Human Tumor necrosis factor (TNF)
CSB-YP023955HU

Target	Product Name	Source	Tag Info	Product Code
IFNG	Recombinant Human Interferon gamma protein (IFNG) (Active)	E.Coli	Tag-Free	CSB-AP002801HU
IFNG	Recombinant Rhesus Macaque Interferon gamma protein (IFNG) (Active)	E.Coli	Tag-Free	CSB-AP003241MOW
IFNG	Recombinant Human Interferon gamma (IFNG) (Active)	E.coli	Tag-Free	CSB-AP004201HU
IL10	Recombinant Human Interleukin-10 protein (IL10) (Active)	E.Coli	Tag-Free	CSB-AP001791HU
Il10	Recombinant Mouse Interleukin-10 (Il10) (Active)	E.coli	Tag-Free	CSB-AP004841MO
IL17A	Recombinant Human Interleukin-17A (IL17A) (Active)	E.coli	Tag-Free	CSB-AP004331HU
IL17A	Recombinant Human Interleukin-17A (IL17A) (Active)	Mammalian cell	C-terminal 6xHis-tagged	CSB-AP004341HU
Il17a	Recombinant Mouse Interleukin-17A (Il17a), partial (Active)	Mammalian cell	C-terminal 6xHis-tagged	CSB-AP004781MO
IL17A	Recombinant Human Interleukin-17A (IL17A) (T26A) (Active)	Baculovirus	N-terminal 6xHis-tagged	CSB-BP624104HU(M)
IL1A	Recombinant Macaca mulatta Interleukin-1 alpha (IL1A) (Active)	E.Coli	Tag-Free	CSB-AP003071MOW
Il1a	Recombinant Mouse Interleukin-1 alpha protein (Il1a) (Active)	E.Coli	Tag-Free	CSB-AP003251MO
IL1B	Recombinant Rhesus Macaque Interleukin-1 beta protein (IL1B) (Active)	E.Coli	Tag-Free	CSB-AP003081MOW
Il1b	Recombinant Mouse Interleukin-1 beta protein (Il1b) (Active)	E.Coli	Tag-Free	CSB-AP003261MO
IL1B	Recombinant Horse Interleukin-1 beta protein (IL1B) (Active)	E.Coli	Tag-Free	CSB-AP003481HO
IL2	Recombinant Human Interleukin-2 protein (IL2) (Active)	E.Coli	Tag-Free	CSB-AP001691HU
IL2	Recombinant Human Interleukin-2 (IL2) (Active)	E.coli	Tag-Free	CSB-AP004381HU
IL2	Recombinant Human Interleukin-2 (IL2) (Active)	Mammalian cell	C-terminal 6xHis-tagged	CSB-AP004501HU
IL2	Recombinant Human Interleukin-2 (IL2) (L100F,R101D,L105V,I106V,I112F) (Active)	Mammalian cell	C-terminal 6xHis-tagged	CSB-AP004711HU
Il2	Recombinant Mouse Interleukin-2 (Il2) (Active)	E.coli	Tag-Free	CSB-AP004821MO
IL2	Recombinant Human Interleukin-2 (IL2) (Active)	Mammalian cell	N-terminal hFc-tagged	CSB-MP011629HU

● 抗體

CD4 Recombinant Monoclonal Antibody
CSB-RA004935A0HU

Tested Applications: ELISA, WB, IHC

CD8A Recombinant Monoclonal Antibody
CSB-RA934881A0HU

Tested Applications: ELISA, IF, FC

IL12B Recombinant Monoclonal Antibody
CSB-RA895985A0HU

Tested Applications: ELISA, WB, IHC, IP

Phospho-STAT3 (S727) Recombinant Monoclonal Antibody
CSB-RA022812A727phHU

Tested Applications: ELISA, WB, IHC, IP

- 重組抗體

Target	Product Name	Species Reactivity	Tested Applications	Code
CD4	CD4 Recombinant Monoclonal Antibody	Human	ELISA, WB, IHC	CSB-RA004935A0HU
CD8A	CD8A Recombinant Monoclonal Antibody	Human	ELISA, WB, IHC, IP	CSB-RA934881A0HU
CRP	CRP Recombinant Monoclonal Antibody	Human	ELISA, IHC	CSB-RA988767A0HU
IL10	IL10 Recombinant Monoclonal Antibody	Human	ELISA	CSB-RA011580A0HU
IL12B	IL12B Recombinant Monoclonal Antibody	Human	ELISA, FC	CSB-RA895985A0HU
IL17A	IL17A Recombinant Monoclonal Antibody	Human	ELISA	CSB-RA624104MA1HU
IL23A	IL23A Recombinant Monoclonal Antibody	Human	ELISA, WB	CSB-RA251959A0HU
IL4	IL4 Recombinant Monoclonal Antibody	Human	ELISA, IHC	CSB-RA240377A0HU
IL6	IL6 Recombinant Monoclonal Antibody	Human	ELISA	CSB-RA011664MA1HU
STAT3	Phospho-STAT3 (S727) Recombinant Monoclonal Antibody	Human	ELISA, WB, IHC, IP	CSB-RA022812A727phHU
STAT3	Phospho-STAT3 (Tyr705) Recombinant Monoclonal Antibody	Human	ELISA, WB, IHC	CSB-RA022812A705phHU
STAT3	STAT3 Recombinant Monoclonal Antibody	Human	ELISA, FC	CSB-RA546821A0HU
STAT3	STAT3 Recombinant Monoclonal Antibody	Human	ELISA, WB, IHC	CSB-RA229700A0HU
STAT3	STAT3 Recombinant Monoclonal Antibody	Human	ELISA, IHC	CSB-RA188270A0HU
STAT3	STAT3 Recombinant Monoclonal Antibody	Human	ELISA	CSB-RA022812MA1HU

- 單克隆抗體

Target	Product Name	Species Reactivity	Tested Applications	Code
CD4	CD4 Monoclonal Antibody	Human,Mouse,Rat	ELISA, IHC	CSB-MA000228
CD4	CD4 Monoclonal Antibody,APC Conjugated	Human	ELISA, IF, FC	CSB-MA043428
CD4	CD4 Monoclonal Antibody,Biotin Conjugated	Human	ELISA, IF, FC	CSB-MA981329
CD4	CD4 Monoclonal Antibody,FITC Conjugated	Human	ELISA, IF, FC	CSB-MA124048
CD4	CD4 Monoclonal Antibody,PE Conjugated	Human	ELISA, IF, FC	CSB-MA260243
CD4	CD4 Monoclonal Antibody,PE-Cy5 Conjugated	Human	ELISA, IF, FC	CSB-MA570802
CD4	CD4 Monoclonal Antibody,Purified	Human	ELISA, FC	CSB-MA783233
CD4	CD4 Monoclonal Antibody,PE Conjugated	Mouse	ELISA, FC	CSB-MA084552
CD8A	CD8A Monoclonal Antibody,APC Conjugated	Human	ELISA, IF, FC	CSB-MA255790
CD8A	CD8A Monoclonal Antibody,Biotin Conjugated	Human	ELISA, IF, FC	CSB-MA955671
CD8A	CD8A Monoclonal Antibody,FITC Conjugated	Human	ELISA, IF, FC	CSB-MA919476
CD8A	CD8A Monoclonal Antibody,PE Conjugated	Human	ELISA, IF, FC	CSB-MA574619
CD8A	CD8A Monoclonal Antibody,PE-Cy5 Conjugated	Human	ELISA, IF, FC	CSB-MA985168
CD8A	CD8A Monoclonal Antibody,Purified	Human	ELISA, FC	CSB-MA927984
CD8A	CD8A Monoclonal Antibody,FITC Conjugated	Mouse	ELISA, IF, FC	CSB-MA248122
CD8A	CD8A Monoclonal Antibody,FITC Conjugated	Mouse	ELISA, FC	CSB-MA833547
CRP	CRP Monoclonal Antibody	Human	ELISA, IHC	CSB-MA027411E0m
CXCL8	CXCL8 Monoclonal Antibody	Human	ELISA, IHC	CSB-MA083271A0m
IFNG	IFNG Monoclonal Antibody	Human	ELISA, IHC	CSB-MA065241A0m
IL1B	IL1B Monoclonal Antibody	Human	ELISA	CSB-MA065741A0m
IL1B	IL1B Monoclonal Antibody	Human	ELISA, WB, IHC, ICC	CSB-MA010884
IL6	IL6 Monoclonal Antibody	Human	ELISA, WB, IHC	CSB-MA067571A0m
TNF	TNF Monoclonal Antibody	Bovine	ELISA	CSB-MA084771A0m
TNF	TNF Monoclonal Antibody	Human,Mouse,Rat	ELISA, WB, IHC	CSB-MA080271
TNF	TNF Monoclonal Antibody	Human,Mouse,Rat	ELISA, WB, IHC	CSB-MA080272

- 多克隆抗體

Target	Product Name	Species Reactivity	Tested Applications	Code
CD4	CD4 Antibody	Human	ELISA, IHC	CSB-PA004935ESR2HU
CD4	Phospho-CD4 (S433) Antibody	Human, Mouse	ELISA, IHC, IF	CSB-PA070257
CD4	CD4 Antibody	Human, Mouse	ELISA, WB, IHC, IF	CSB-PA001453
CD4	CD4 Antibody	Human, Mouse, Rat	ELISA, WB	CSB-PA004935GA01HU
CD8A	CD8A Antibody	Human	ELISA, IHC	CSB-PA004966LA01HU
CRP	CRP Antibody	Human	ELISA, WB, IHC	CSB-PA06079A0Rb
crp	crp Antibody	Escherichia coli	ELISA	CSB-PA359785LA01ENV
CRP	CRP Antibody	Human, Rat	ELISA, WB	CSB-PA005116
CRP	CRP Antibody	Human	ELISA, WB, IHC	CSB-PA181901
CRP	CRP Antibody	Human	ELISA, WB, IHC	CSB-PA790121
CXCL8	CXCL8 Antibody	Dog	ELISA	CSB-PA011671YA01DO
CXCL8	CXCL8 Antibody	Human	ELISA, WB, IHC	CSB-PA08327A0Rb
CXCL8	CXCL8 Antibody	Gallus gallus	ELISA	CSB-PA15789A0Rb
CXCL8	CXCL8 Antibody	Human	ELISA, IF	CSB-PA08329A0Rb
CXCL8	CXCL8 Antibody	Human	ELISA, WB, IHC	CSB-PA003036
CXCL8	CXCL8 Antibody	Human	ELISA, WB	CSB-PA004977
CXCL8	CXCL8 Antibody	Human	ELISA, IHC	CSB-PA009564
CXCL8	CXCL8 Antibody	Human	ELISA, IHC	CSB-PA011671GA01HU
IER3	IER3 Antibody	Human	ELISA, IF	CSB-PA011002LA01HU
IFNG	IFNG Antibody	Human	ELISA, WB	CSB-PA011050HA01HU

● ELISA試劑盒

Target	Product Name	Sample Types	Detection Range	Code
CD4	Human cluster of differentiation 4,CD4 ELISA Kit	serum, plasma	0.625 ng/mL-40 ng/mL	CSB-E08956h
CD4	Rat cluster of differentiation 4,CD4 ELISA Kit	serum, plasma, tissue homogenates	0.78 U/mL-50 U/mL	CSB-E12928r
CD4	Chicken Cluster of Differentiation 4(CD4) ELISA Kit	serum, plasma, tissue homogenates	3.125 ng/mL-800 ng/mL	CSB-E13114C
CD8A	Human Cluster of differentiation 8,CD8 ELISA Kit	serum, plasma, cell culture supernates, tissue homogenates	62.5 U/mL-4000 U/mL	CSB-E12707h
CRP	Mouse C-Reactive Protein,CRP ELISA Kit	serum, plasma, tissue homogenates	5 ng/mL-4000 ng/mL	CSB-E07923m(1)
CRP	Rabbit C-Reactive Protein,CRP ELISA Kit	serum, plasma	7.8 pg/mL-2000 pg/mL	CSB-E06847Rb
CRP	Rat C-Reactive Protein,CRP ELISA Kit	serum, plasma, cell culture supernates, tissue homogenates, cell lysates	31.25 ng/mL-2000 ng/mL	CSB-E07922r
CRP	Mouse C-Reactive Protein,CRP ELISA Kit	serum, plasma, cell culture supernates, tissue homogenates	15.6 ng/mL-1000 ng/mL	CSB-E07923m
CRP	Pig C-reactive protein,CRP ELISA Kit	serum, plasma, tissue homogenates	0.625 ng/mL-40 ng/mL	CSB-E08163p
CRP	Bovine C-reactive protein,CRP ELISA Kit	serum, plasma	1.25 ng/mL-80 ng/mL	CSB-E08577b
CRP	Canine C-Reactive Protein,CRP ELISA Kit	serum, plasma, cell culture supernates	0.312 μg/mL-20 μg/mL	CSB-E14262c
CRP	Sheep C-reactive protein(CRP) ELISA Kit	serum, plasma, tissue homogenates, cell lysates	0.625 μg/mL-40 μg/mL	CSB-E15081Sh
CRP	Hamster C-reactive protein(CRP) ELISA Kit	serum, plasma, tissue homogenates	12.5 ng/mL-800 ng/mL	CSB-EL005991HA
CXCL8	Human Interleukin 8,IL-8 ELISA KIT	serum, cell culture supernates, saliva, urine, cerebrospinal fluid (CSF), tissue homogenates, cell l	31.25 pg/mL-2000 pg/mL	CSB-E04641h
CXCL8	Pig interleukin 8,IL-8 ELISA Kit	serum, plasma, cell culture supernates, tissue homogenates	125 pg/mL-8000 pg/mL	CSB-E06787p
CXCL8	Dog Interleukin-8,IL-8 ELISA Kit	serum, plasma, cell culture supernates, tissue homogenates	0.312 ng/mL-20 ng/mL	CSB-E08052c
CXCL8	Rabbit Interleukin 8,IL-8 ELISA Kit	serum, plasma, tissue homogenates	23.5 pg/mL-1500 pg/mL	CSB-E06905Rb
CXCL8	Monkey Interleukin-8,IL-8 ELISA Kit	serum, plasma, cell culture supernates, tissue homogenates	31.25 pg/mL-2000 pg/mL	CSB-E08051Mo
CXCL8	Bovine Interleukin 8,IL-8 ELISA Kit	serum, plasma, tissue homogenates	50 pg/mL-2000 pg/mL	CSB-E13052B
CXCL8	Guinea pig Interleukin 8,IL-8 ELISA Kit	serum, plasma, tissue homogenates	31.25 pg/mL-2000 pg/mL	CSB-E13096Gp