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消化系統(tǒng)疾病

消化系統(tǒng)疾病是一類影響消化道結(jié)構(gòu)和功能的各種病癥,包括食管、胃、小腸、大腸、肝臟、膽囊、胰腺等器官的疾病。這些疾病可能由多種因素引起,包括感染、自身免疫反應(yīng)、遺傳、生活方式和環(huán)境因素等。消化系統(tǒng)疾病的癥狀多樣,從輕微的不適到嚴(yán)重的疼痛、出血或營(yíng)養(yǎng)不良等。常見(jiàn)的消化系統(tǒng)疾病包括胃炎、消化性潰瘍、胃癌、肝炎、肝硬化、胰腺炎、炎癥性腸病等。

近年來(lái),消化系統(tǒng)疾病的藥物研發(fā)取得了顯著進(jìn)展。例如,針對(duì)消化性潰瘍的治療,新型藥物如鉀離子競(jìng)爭(zhēng)性酸阻滯劑伏諾拉生(沃諾拉贊)已經(jīng)上市,顯示出良好的療效和安全性。此外,針對(duì)胃食管反流?。℅ERD),新型抑酸藥物的研發(fā)也在進(jìn)行中,旨在提供更好的治療效果和減少副作用。

在消化道腫瘤的治療方面,免疫治療和靶向治療技術(shù)快速發(fā)展。例如,PD-1/PD-L1抗體和部分靶向治療藥物(如貝伐珠單抗和西妥昔單抗)已被批準(zhǔn)用于晚期消化道腫瘤治療。

消化系統(tǒng)疾病靶點(diǎn)相關(guān)產(chǎn)品推薦

● 靶點(diǎn)蛋白

CSB-MP619964HU1 Activity Verified

Measured by its binding ability in a functional ELISA. Immobilized PD-1 at 2 μg/ml can bind Anti-PD-1 recombinant antibody, the EC50 of human PD-1 protein is 6.087-7.854 ng/ml.

CSB-MP007763HU Activity Verified

Measured by its binding ability in a functional ELISA. Immobilized HER2 at 2 μg/ml can bind Trastuzumab, the EC50 is 2.179-2.825 ng/ml.

CSB-MP007479HU Activity Verified

Human EGF protein captured on COOH chip can bind Human EGFR protein, his and Myc tag (CSB-MP007479HU) with an affinity constant of 11.9nM as detected by LSPR Assay.

CSB-MP005498HU(A5) Activity Verified

Measured by its binding ability in a functional ELISA. Immobilized human CLDN18.2 (CSB-MP005498HU(A5)) at 5 μg/ml can bind anti-CLDN18.2 recombinant Monoclonal Antibody (CSB-RA005498A1HU), the the EC50 is 5.225-9.256 ng/ml.

CSB-MP878942HU1 Activity Verified

Measured by its binding ability in a functional ELISA. Immobilized PD-L1 at 2 μg/ml can bind Anti- PD-L1 mouse monoclonal antibody(CSB-MA878942A1m, antigen from E.coli), the EC50 of human PD-L1 protein is 1.252-1.653 ng/mL

CSB-MP006163HU1 Activity Verified

Measured by its binding ability in a functional ELISA. Immobilized CD152 at 2 μg/ml can bind Anti-CD152 rabbit monoclonal antibody (CSB-RA213310A0HU), the EC50 of human CD152 protein is 27.14-34.82 ng/ml.

CSB-MP009514HUb1 Activity Verified

Measured by its binding ability in a functional ELISA. Immobilized Human GLP1R at 2 μg/mL can bind Anti-GLP1R recombinant antibody (CSB-RA009514MA1HU), the EC50 is 54.54-94.23 ng/mL.

CSB-MP023997HU1 Activity Verified

Measured by its binding ability in a functional ELISA. Immobilized TNFSF9 at 2 μg/ml can bind TNFRSF9(CSB-MP023984HU1), the EC50 is 2.671-3.702 ng/mL

產(chǎn)品名稱 貨號(hào) 靶點(diǎn) 來(lái)源 蛋白標(biāo)簽
Recombinant Human Programmed cell death 1 ligand 1 (CD274), partial (Active) CSB-MP878942HU1 CD274 Mammalian cell C-terminal hFc-tagged
Recombinant Human CD276 antigen (CD276), partial (Active) CSB-MP733578HU CD276 Mammalian cell C-terminal hFc-Myc-tagged
Recombinant Human Tumor necrosis factor receptor superfamily member 5 (CD40), partial (Active) CSB-AP005181HU CD40 Mammalian cell C-terminal Fc-tagged
Recombinant Human Tumor necrosis factor receptor superfamily member 5 (CD40), partial (Active) CSB-MP004936HU1 CD40 Mammalian cell C-terminal hFc-tagged
Recombinant Human CD40 ligand (CD40LG), partial (Active) CSB-AP005191HU CD40LG E.coli Tag-Free
Recombinant Human CD40 ligand (CD40LG), partial (Active) CSB-MP004937HU3 CD40LG Mammalian cell N-terminal hFc-Flag-tagged
Recombinant Human CD44 antigen (CD44), partial (Active) CSB-MP004938HU(F1) CD44 Mammalian cell C-terminal hFc-tagged
Recombinant Human CD44 antigen (CD44), partial, Biotinylated (Active) CSB-MP004938HU(F1)j1-B CD44 Mammalian cell C-terminal mFc-Avi-tagged
Recombinant Macaca fascicularis CD44 antigen (CD44), partial (Active) CSB-MP4290MOV CD44 Mammalian cell C-terminal 10xHis-tagged
Recombinant Human Leukocyte surface antigen CD47 (CD47), partial (Active) CSB-AP005201HU CD47 Mammalian cell C-terminal 6xHis-tagged
Recombinant Human Leukocyte surface antigen CD47 (CD47), partial (Active) CSB-AP005211HU CD47 Mammalian cell C-terminal Fc-tagged
Recombinant Human Leukocyte surface antigen CD47 (CD47), partial (Active) CSB-MP004940HU CD47 Mammalian cell C-terminal hFc-tagged
Recombinant Human T-lymphocyte activation antigen CD86 (CD86), partial (Active) CSB-AP005161HU CD86 Mammalian cell C-terminal 6xHis-tagged
Recombinant Human Cadherin-17 (CDH17), partial (Active) CSB-MP613267HU CDH17 Mammalian cell C-terminal?10xHis-tagged
Recombinant Macaca fascicularis Cadherin 17 (CDH17), partial (Active) CSB-MP4664MOV CDH17 Mammalian cell C-terminal 10xHis-tagged
Recombinant Human Carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) (E398K) (Active) CSB-MP005165HU CEACAM5 Mammalian cell C-terminal?10xHis-tagged
Recombinant Human Carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6) (Active) CSB-MP005166HU CEACAM6 Mammalian cell C-terminal 10xHis-tagged
Recombinant Macaca fascicularis Claudin (CLDN18)-VLPs (Active) CSB-MP4304MOV CLDN18 Mammalian cell N-terminal 6xHis-tagged (This tag can be tested only under denaturing conditions)
Recombinant Mouse Claudin-18 (Cldn18)-VLPs (Active) CSB-MP005498MO(F3) Cldn18 Mammalian cell N-terminal 6xHis-tagged (This tag can be tested only under denaturing conditions)
Recombinant Human Granulocyte-macrophage colony-stimulating factor receptor subunit alpha (CSF2RA), partial (Active) CSB-AP003591HU CSF2RA Mammalian cell C-terminal 6xHis-tagged

● 穩(wěn)定細(xì)胞株

CSB-SC009705HU2
CSB-SC009705HU2 FACS

CT26/Human GPC3 Stable Cell Line

Untransfected CT26 cells (green line) and transfected Human GPC3 CT26 Stable cells (red line) were stained with anti-GPC3 antibody (CSB-RA009705A1HU) (2μg/1*106 cells), washed and then followed by APC-conjugated anti-Human IgG Fc antibody and analyzed with flow cytometry.

CSB-SC613267HU2
CSB-SC613267HU2 FACS

HEK293T/Human CDH17 Stable Cell Line

Untransfected HEK293T cells (green line) and transfected Human CDH17 HEK293T stable cells (red line) were stained with anti-CDH17 antibody (CSB-RA613267MA1HU) (2μg/1*106 cells), washed and then followed by FITC-conjugated anti-Human IgG Fc antibody and analyzed with flow cytometry.

● 重組抗體

CDH17 Recombinant Monoclonal Antibody
CSB-RA613267MA1HU
CSB-RA613267MA1HU FC

Untransfected HEK293T cells surface (green line) and transfected Human CDH17 HEK293T stable cells surface (red line) were stained with anti-CDH17 antibody (2μg/1*106 cells).

EGFR Recombinant Monoclonal Antibody
CSB-RA159341A0HU
CSB-RA159341A0HU FC

Overlay histogram showing Jurkat cells stained with CSB-RA159341A0HU (red line) at 1:50.

FLT1 Recombinant Monoclonal Antibody
CSB-RA215817A0HU
CSB-RA215817A0HU FC

Overlay Peak curve showing MCF-7 cells stained with CSB-RA940669A0HU (red line) at 1:50.

MADCAM1 Recombinant Monoclonal Antibody
CSB-RA215817A0HU
CSB-RA215817A0HU FC

Overlay Peak curve showing PC3 cells surface stained with CSB-RA215817A0HU (red line) at 1:100.

產(chǎn)品名稱 貨號(hào) 靶點(diǎn) 反應(yīng)種屬 應(yīng)用范圍
ALB Recombinant Monoclonal Antibody CSB-RA264109A0HU ALB Human ELISA, FC
CD247 Recombinant Monoclonal Antibody CSB-RA244537A0HU CD247 Human ELISA, FC
CD274 Recombinant Monoclonal Antibody CSB-RA977797A0HU CD274 Human ELISA, WB, IHC
CD274 Recombinant Monoclonal Antibody CSB-RA878942MA1HU CD274 Human ELISA, IHC, FC
CD40 Recombinant Monoclonal Antibody CSB-RA004936MA1HU CD40 Human ELISA, IF, FC
CD44 Recombinant Monoclonal Antibody CSB-RA004938A0HU CD44 Human ELISA, WB, IHC
CD44 Recombinant Monoclonal Antibody CSB-RA292372A0HU CD44 Human ELISA, WB, IHC, IF, FC
CD44 Recombinant Monoclonal Antibody CSB-RA004938MA1HU CD44 Human ELISA, FC
CD47 Recombinant Monoclonal Antibody CSB-RA802124A0HU CD47 Human ELISA, WB, IHC, IF
CD86 Recombinant Monoclonal Antibody CSB-RA004965A0HU CD86 Human ELISA, WB
CDH17 Recombinant Monoclonal Antibody CSB-RA613267MA1HU CDH17 Human ELISA,F(xiàn)C
CEACAM5 Recombinant Monoclonal Antibody CSB-RA005165MA3HU CEACAM5 Human ELISA, IF, FC
CEACAM5 Recombinant Monoclonal Antibody CSB-RA005165MA1HU CEACAM5 Human ELISA
CLDN18 Recombinant Monoclonal Antibody CSB-RA005498A2HU CLDN18 Human ELISA, FC
Claudin-18.2 Recombinant Monoclonal Antibody CSB-RA005498A1HU CLDN18 Human ELISA, FC
CTLA4 Recombinant Monoclonal Antibody CSB-RA213310A0HU CTLA4 Human ELISA, IHC
CTLA4 Recombinant Monoclonal Antibody CSB-RA006163MA1HU CTLA4 Human, Mouse ELISA, WB, IF, FC
CXCL10 Recombinant Monoclonal Antibody CSB-RA903061A0HU CXCL10 Human ELISA, IHC
CXCR4 Recombinant Monoclonal Antibody CSB-RA569311A0HU CXCR4 Human ELISA, IF
CXCR4 Recombinant Monoclonal Antibody CSB-RA006254MA01HU CXCR4 Human ELISA

● ELISA試劑盒

產(chǎn)品名稱 貨號(hào) 靶點(diǎn) 檢測(cè)范圍 靈敏度
Human Alpha-fetoprotein,AFP ELISA Kit CSB-E04770h AFP 1.563 ng/mL-100 ng/mL 1.332 ng/mL
Mouse Alpha-fetoprotein,AFP ELISA Kit CSB-E08282m AFP 1.23 ng/ml-900 ng/ml. 1.23 ng/ml.
Rat Alpha-fetoprotein,AFP ELISA Kit CSB-E08281r AFP 15.6 pg/mL-1000 pg/mL 3.9 pg/mL
Pig Alpha-fetoprotein(AFP) ELISA kit CSB-EL001421PI AFP 3.12 ng/mL-200 ng/mL 0.78 ng/mL
Bovine Albumin(Alb) ELISA kit CSB-E08664b ALB 0.313 μg/mL-80 μg/mL 0.148 μg/mL
Mouse Albumin (Alb)ELISA Kit CSB-E13878m ALB 0.781 μg/mL-200 μg/mL 0.110 μg/mL
Dog Albumin(Alb) ELISA Kit CSB-E15757c ALB 0.273 μg/mL-35 μg/mL 0.266 μg/mL
Sheep Albumin (Alb)ELISA Kit CSB-E15839Sh ALB 350 μg/mL-21.88 μg/mL 5.5 μg/mL
Horse Albumin(Alb) ELISA Kit CSB-E16205Hs ALB 1.25 μg/mL-80 μg/mL 1.247 μg/mL
Pig Albumin (Alb) ELISA Kit CSB-E16207p ALB 0.03 μg/mL-7000 μg/mL 0.03 μg/mL
Goat Albumin (Alb)ELISA Kit CSB-E15758G ALB 0.17 μg/mL-350 μg/mL 0.17 μg/mL
Guinea Pig Albumin(Alb) ELISA kit CSB-E15765Gp ALB 0.156 μg/mL-10 μg/mL 0.09 μg/mL
Rabbit Albumin(Alb) ELISA Kit CSB-E16204Rb ALB 0.273 μg/mL-70 μg/mL 0.117 μg/mL
Mouse Membrane primary amine oxidase(AOC3) ELISA kit CSB-EL001855MO AOC3 1.25 ng/mL-80 ng/mL 0.31 ng/mL
Rat Membrane primary amine oxidase(AOC3) ELISA kit CSB-EL001855RA AOC3 7.8 ng/mL-500 ng/mL 1.95 ng/mL
Human T-cell surface glycoprotein CD3 zeta chain (CD247) ELISA kit CSB-EL004904HU CD247 0.156 ng/mL-10 ng/mL 0.039 ng/mL
Human Programmed Death Ligand-1(PD-L1/CD274) ELISA Kit CSB-E13644h CD274 15.6 pg/mL-1000 pg/mL 3.9 pg/mL
Mouse Programmed cell death 1 ligand 1(CD274) ELISA kit CSB-EL004911MO CD274 31.25 pg/mL-2000 pg/mL 7.81 pg/mL
Human Soluble CD276,sCD276/sB7-H3 ELISA Kit CSB-E14285h CD276 3.12 ng/mL-200 ng/mL 0.78 ng/mL
Human soluble cluster of differentiation 28,sCD28 ELISA Kit CSB-E09296h CD28 0.625 ng/mL-40 ng/mL 0.156 ng/mL
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